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ProteomicsMetDNA3 Exploris 480 datasets (Knowledge and Data-driven Two-layer Networking for Accurate Metabolite Annotation in Untargeted Metabolomics)
MetDNA3 Exploris 480 datasets were generated using the high-resolution Thermo Fisher Exploris 480 mass spectrometry platform and annotated with MetDNA3, which integrates a Knowledge- and Data-driven Two-layer Networking strategy for accurate metabolite annotation in untargeted metabolomics. This dat...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Mus Musculus (ncbitaxon:10090) 
2025-05-19 | MSV000097913 | MassIVE
Proteomics15 cm Aurora Gen3 column benchmarking on an Exploris 480
A comprehensive proteome map is essential to elucidate molecular pathways and protein functions. Although great improvements in sample preparation, instrumentation and data analysis already yield-ed impressive results, current studies suffer from a limited proteomic depth and dynamic range there-for...
ORGANISM(S): Homo sapiens (Human) 
2024-02-13 | PXD045457 | Pride
Vanquish neo Orbitrap exploris 480 Trap-and-elute 
ProteomicsPR8 Sbmut HA library characterization Heaton
LC-MS/MS analysis of HA peptides using DIA and DiA-NN on an Exploris 480.
ORGANISM(S): Homo sapiens (Human) 
2024-04-05 | PXD048318 | Pride
Dia Ha peptidome Exploris 
ProteomicsExosomal protein Profiling in Plasma of DOCA-Salt-Induced Hypertensive and Control Mice
This study aimed to profile exosomal protein extracted from plasma of male and female mice treated with DOCA-salt (a model for hypertension) and corresponding baseline controls. The isolated exosomal proteins were sequenced using using LC-MS/MS (Orbitrap Exploris 480+FAIMS Pro). This approach may he...
ORGANISM(S): Mus musculus (Mouse) 
2026-02-09 | PXD068025 | Pride
Hypertensive mice Proteomics Extracellular vesicles 
ProteomicsComparison of DDA (Orbitrap Exploris 480) and DIA (timsTOF Pro 2) phosphoproteomics
In this experiment, 3 replicate phosphopeptide enrichments using titanium dioxide spin tips (GL Science) of the filamentous fungus Magnaporthe oryzae were measured on a) Orbitrap Exploris 480 in DDA and b) timsTOF Pro 2 in DIA for comparison of model/acquisition type differences.
ORGANISM(S): Cellular Organisms 
2023-04-13 | PXD038605 | JPOST Repository
MetabolomicsPlasma metabolomic profiling reveals altered metabolic pathways associated with idiopathic hyperaldosteronism
This study investigated plasma metabolic alterations associated with idiopathic hyperaldosteronism using untargeted liquid chromatography coupled with high-resolution mass spectrometry. Plasma samples from patients with idiopathic hyperaldosteronism and healthy controls were analyzed using a Vanquis...
2026-08-07 | MTBLS15210 | MetaboLights
ProteomicsWhat does next generation Mass Spectrometry offer for proteomics? A comprehensive platform comparison
Next-generation mass spectrometry platforms (Orbitrap Astral, timsTOF Ultra) are reshaping proteomics by enhancing analytical depth and sensitivity. We compared these platforms against Orbitrap Exploris 480 using neonatal mouse lung tissue from a bronchopulmonary dysplasia model (n=12), employing fo...
ORGANISM(S): Mus musculus (Mouse) 
2026-04-02 | PXD057442 | Pride
Mouse Lung Bronchopulmonary dysplasia Platform comparison 
ProteomicsUltra-sensitive proteomics using second generation micro pillar array LC technology with Orbitrap Exploris™ 480 and FAIMS
In the light of the ongoing single-cell revolution, scientific disciplines are combining forces with the ultimate goal to retrieve as much relevant data as possible from trace amounts of biological material. For single cell proteomics, this implies optimizing the entire workflow from initial cell is...
ORGANISM(S): Homo sapiens (Human) 
2021-06-28 | PXD024017 | Pride
Micro pillar Low-input proteomics Single sell proteomics 
MetabolomicsIntegrated transcriptome and metabolome analysis reveals the regulatory mechanism underlying fluoride tolerance in XSKD silkworm strain
XueSong KD (XSKD) is a fluoride-tolerant Bombyx mori strain that grows normally under long-term fluoride exposure, whereas its molecular tolerance mechanism remains elusive. Herein, we performed combined transcriptomic and untargeted metabolomic profiling using pre-molt fourth-instar XSKD larvae fed...
2026-07-07 | MTBLS14966 | MetaboLights
ProteomicsAn oligosaccharyltransferase from Leishmania donovani increases the N-glycan occupancy on plant-produced IgG1
The monoclonal antibodies rituximab and cetuximab were transiently expressed in leaves of Nicotiana benthamiana plants and purified by affinity chromatography using protein A. Purified antibodies were analysed by intact MS. Purified antibodies were also subjected to trypsin digestion followed by LC-...
ORGANISM(S): Nicotiana benthamiana 
2023-07-31 | PXD043623 | Pride
Recombinant protein Antibody Oligosaccharyltransferase N-glycosylation 
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