Eye wash - OmicsDI

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Transcriptomics (747)
Genomics (72)
Unknown (41)
Proteomics (29)
Metabolomics (5)
Other (2)

Organisms

Mus musculus (232)
Homo sapiens (146)
Drosophila melanogaster (59)
Rattus norvegicus (49)
Schizosaccharomyces pombe (28)
Danio rerio (28)
Saccharomyces cerevisiae (24)
Salmo salar (22)
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Caenorhabditis elegans (14)
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Oncorhynchus mykiss (11)
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Arabidopsis thaliana (8)
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environmental samples (2)
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Shewanella oneidensis MR-1 (2)
Cryptopygus antarcticus (2)
Ambystoma mexicanum (2)

Organisms

Danio rerio (2)
Mus musculus (2)
Homo sapiens (1)

Repository

biostudies-arrayexpress (823)
pride (23)
ENA (6)
MassIVE (5)
MetaboLights (5)

Tissue

Retina (8)
Visual cortex (2)
Tear (2)
Retinal pigment epithelial cell (2)
Retinal ganglion cell (1)
Left ventricle (1)
Lens nucleus (1)
Conjunctiva (1)
Photoreceptor cell (1)
Extracellular space (1)
Cornea (1)
Eye (1)
Stem cell (1)
Heart (1)
Brain (1)
Blood plasma (1)
Epithelial cell (1)

Disease

Normal (9)
Oropharynx squamous-cell carcinoma in DiseaseLocation oropharynx has DiseaseStaging lymph node negative (N0) (1)
T. circumcincta infection (1)
Uninfected (1)
Dengue 2 (JAM1409) infected (1)
Embryonic lethal at day 8.5 to 9.5 (1)
Infected with IBDV strain F52/70 (1)
No injury (1)
Carotid artery disease: ASYMPTOMATIC high-grade inner carotid artery stenosis (1)
Apparently healthy (1)
Infected (1)
Marsh 3 (1)
Dukes D primary colon cancer (1)
Mock infected (1)
Colon cancer metastasis (1)
Invasive lobular carcinoma (1)
Hyperglycaemic (1)
Not infected (1)
Infant SGA (1)
Temporal lobe epilepsy (1)
Chronic myeloid leukemia (1)
Benign adenoma (1)
Mastitis (1)
Cancer (1)
Chicken Anaemia Virus infected (1)
Hypertensive (1)
N/a (1)
Osteosarcoma (1)
5 days post MHV infection (1)
Keratitis (1)

Technology Type

Mass Spectrometry (23)
Shotgun proteomics (10)
Bottom-up proteomics (8)
Data-dependent acquisition (5)
Mass spectrometry (3)
NMR spectroscopy (2)
Gel-based experiment (2)
SRM/MRM (2)
Top-down proteomics (1)
Affinity purification coupled with mass spectrometry proteomics (1)
Data-independent acquisition (1)
SWATH MS (1)

Instrument Platform

Axon GenePix 4000B scanning hardware (13)
G2565AA DNA microarray scanner [Agilent] (7)
ScanArray 5000 [PerkinElmer] (5)
Scanning hardware (5)
Illumina NovaSeq 6000 (5)
Genepix (4)
GenePix Personal 4100A [Axon Instruments] (3)
Chemostat (3)
NextSeq 2000 (3)
NextSeq 500 (3)
Illumina BeadArray reader (2)
DNA Microarray Scanner BA [Agilent Technologies] (2)
ScanArray Express HT [PerkinElmer] (2)
NA (2)
Illumina MiSeq (2)
PromethION (1)
Tecan LS 300 scanner (1)
GenePix 4100A (Molecular Device) (1)
Microcentrifuge (1)
Axon Instruments GenePix 4000B scanner (1)
Axon GenePix4000B (1)
(Make:PerkinElmer,Model:ScanArray 4000XL) (1)
Agilent Technologies SureScan Microarray Scanne (1)
SureScan Dx (1)
Biotech Photometer (1)
Affymetrix 428 (1)
Agilent DNA Microarray Scanner (1)
Axon 4000B (1)
GeneChip Scanner 3000 [Affymetrix] (1)
GenePix Professional 4200A [Axon Instruments] (1)

Publication Date

2013 (113)
2010 (110)
2012 (84)
2014 (83)
2015 (73)
2011 (64)
2016 (53)
2009 (43)
2008 (41)
2004 (31)
2007 (29)
2006 (24)
2005 (23)
2026 (13)
2025 (11)
2022 (11)
2017 (11)
2019 (10)
2023 (9)
2024 (6)
2018 (6)
2003 (4)
2021 (2)
2020 (2)

CHEBI ID

CHEBI:15366 (2)
CHEBI:16870 (2)
CHEBI:30751 (2)
CHEBI:16264 (2)
CHEBI:20067 (2)
CHEBI:16704 (2)
CHEBI:18132 (2)
CHEBI:17287 (2)
CHEBI:15354 (2)
CHEBI:16919 (2)
CHEBI:18012 (2)
CHEBI:30769 (2)
CHEBI:183642 (1)
CHEBI:86637 (1)
CHEBI:139294 (1)
CHEBI:183515 (1)
CHEBI:86622 (1)
CHEBI:86592 (1)
CHEBI:91172 (1)
CHEBI:183516 (1)
CHEBI:139241 (1)
CHEBI:91209 (1)
CHEBI:91204 (1)
CHEBI:167531 (1)
CHEBI:167538 (1)
CHEBI:167540 (1)
CHEBI:16673 (1)
CHEBI:136772 (1)
CHEBI:137977 (1)
CHEBI:71498 (1)

Metabolite Name

3-dihydroxybenzoic acid (1)
G(8-O-4)G(8-O-4)S(8-8)S (1)
G(8-O-4)S(8-8)S(8-O-4)G (1)
G(8-O-4)S(8-O-4)S(8-8)S (1)
G(8-O-4)G(8-O-4)S(8-5)G (1)
G(8-O-4)S (1)
G(8-O-4)S(8-5)G (1)
Salicyloylsalicin-C7H12O7 (1)
7-O-Methylnaringenin-7-furanosyl-(1-6)-glucopyranoside (1)
HCH-salicortin (1)
Grandidentatin like (1)
Aromadendrin 7-O-glucoside (1)
5-hydroxyconiferyl alcohol derivative (1)
G(t8-O-4)G (1)
Salicyloylsalicin (1)
G(8-O-4)G (1)
Coniferyl aldehyde-5-hydroxyconiferyl aldehyde (1)
Scopoletin glucoside (1)
2-O-acetylsalicin (1)
1-O-(4-Coumaroyl)-beta-D-glucose (1)
Scopoletin-C5H9O5 (1)
HCH(like) glucoside (1)
Salirepin (1)
IsoSalicin (1)
2,5-dihydroxybenzoic acid 5-O-beta-D-glucoside (1)
Galloylglucoside (1)
Syringic acid glucoside (1)
Salicylic acid glucoside (1)
4-Hydroxybenzoate-O-glucoside (1)
Vanillic acid glucoside (1)

First Public Date

2024 (2)
2026 (1)
2020 (1)
2017 (1)
2014 (1)

Study type

Transcription profiling by array (617)
ChIP-seq (60)
RNA-seq of coding RNA (28)
RNA-seq of non coding RNA (21)
ChIP-chip by array (16)
ChIP-chip by tiling array (15)
Unknown experiment type (11)
Comparative genomic hybridization by array (11)
Other (8)
Methylation profiling by array (4)
Methylation profiling by high throughput sequencing (4)
Proteomic profiling by array (3)
Transcription profiling by tiling array (2)
RNAi profiling by array (2)
ATAC-seq (2)
RIP-seq (2)
MicroRNA profiling by array (2)
DNA-seq (2)
RNA-seq of coding RNA from single cells (2)
Cell line - One-color microarray (1)
High-throughput sequencing (1)
Ribo-seq (1)
Single nucleus RNA sequencing (1)

Release Date

2013 (114)
2010 (110)
2014 (84)
2012 (84)
2015 (72)
2011 (65)
2016 (53)
2009 (43)
2008 (41)
2004 (31)
2007 (29)
2006 (24)
2005 (23)
2023 (14)
2017 (14)
2022 (13)
2026 (8)
2021 (7)
2018 (7)
2025 (6)
2020 (6)
2019 (6)
2024 (5)
2003 (5)

Lab affiliation

Boston Children's Hospital (3)
1Brunason Center for Translational Vision Research, Department of Ophthalmology and Visual Sciences, Gavin Herbert Eye Institute, University of California, Irvine, Irvine, CA, 92697, USA; 2Department of Physiology and Biophysics, University of California, Irvine, Irvine, CA, 92697, USA; 3Department of Chemistry, University of California, Irvine, Irvine, CA, 92697, USA; Department of Molecular Biology and Biochemistry, University of California, Irvine, Irvine, CA, 92697, USA (1)
Bascom Palmer Eye Institute, Department of Ophthalmology, Miller School of Medicine at University of Miami, Miami, FL 33136, USA +1 (305) 4824103 (1)
Dr. Sailaja V Elchuri,Department of Nanotechnology, VisionResearch Foundation, Sankara Nethralaya, 18-college Road, Nungambakkam, Chennai 600006 India (1)
Neurobiology, Neurodegeneration and Repair Laboratory, National Eye Institute, National Institutes of Health, Bethesda, MD , USA. (1)
Molecular and Cellular Biology Department, University of Guelph (1)
1. Gavin Herbert Eye Institute - Center for Translational Vision Research, Department of Ophthalmology, University of California Irvine, CA, 92697, USA 2. Department of Physiology and Biophysics, School of Medicine, University of California Irvine, CA (1)
1. Shengli Clinical Medical College of Fujian Medical University, Fujian Provincial Hospital, Fuzhou University Affiliated Provincial Hospital, Department of Neurology, Fuzhou 350108, China 2.School of Medicine, The Chinese University of Hong Kong, Shenzhen 518172, China (1)
Associate Professor of Medicine, Division of Infectious Diseases, Department of Medicine, Washington Univerisity in St Louis (1)
Senior Principal Research Scientist, Head, Ocular Proteomics Platform Singapore Eye Research Institute Singapore (1)
University of Colorado Skaggs School of Pharmacy (1)
1.Center for Translational Vision Research, Gavin Herbert Eye Institute, Department of Ophthalmology, University of California-Irvine, Irvine, CA 92697, USA 2.Department of Ophthalmic Research, Cleveland Clinic, Cleveland, OH 44195, USA 3.Department of Physiology & Biophysics, School of Medicine, University of California-Irvine, Irvine, CA 92697, USA (1)
IUSM Biochemistry and Molecular Biology, Center for Proteome Analysis, Indianapolis, IN (1)
Singapore Eye Research Institute (1)
Department of Biology Wanek School of Natural Sciences High Point University 1 N University Pkwy High Point, NC 27368 USA (1)
Professor and Robert A. Welch Chair in Biochemistry Department of Pharmacology and Neuroscience UNT Helth at Fort Worth (1)
Professor and Robert A. Welch Chair in Biochemistry Department of Pharmacology and Neuroscience UNT Health at Fort Worth (1)
Byers Eye Institute, Stanford University (1)
Core Facility Proteomics, Department of Clinical Chemistry, University Medical Center Goettingen, Germany (1)
Aarhus University Department of Biomedicine Aarhus Denmark (1)
UCSF (1)

Tags

xref:PubMed:38712203 (2)
xref:PubMed:16723463 (1)
xref:PubMed:29048427 (1)
xref:PubMed:32596237 (1)

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Proteomic profiling of murine ocular surface during Pseudomonas aeruginosa infection

Mass spectrometry-based proteomics by bottom-up approaches enables the unbiased and sensitive profiling of cellular proteomes and extracellular environments. Recent technological and bioinformatic advances permit identifying of dual biological systems in a single experiment, supporting investigation...

ORGANISM(S): Mus musculus (Mouse) Pseudomonas aeruginosa PAO1

2020-01-09 | PXD015362 | Pride

Expression analysis of WASH knockout LT-HSC cells

Investigation of whole genome gene expression level changes in WASH knockout LT-HSCs, compared to the WASH WT strain. To find the reason that causes LT-HSC abnormal. Gene expression profiling using sorted LT-HSC samples from C57/BL6 strain. Total RNA extracted from WASH control (isolated RNA fr...

ORGANISM(S): Mus musculus

2014-05-17 | E-GEOD-57741 | biostudies-arrayexpress

Proteomic analysis of the thryoid eye disease tear film

Thyroid eye disease (TED) is a complex autoimmune disease that is often disfiguring and sight threatening. Recent advances have shifted the treatment paradigm from traditional immunosuppressive therapies such as corticosteroids to targeted biologic agents, such as teprotumumab (TMB; anti-IGF-1R) whi...

ORGANISM(S): Homo sapiens (Human)

2026-06-08 | PXD066511 | Pride

Thyroid eye disease Teprotumumab Tears Ted

Comparison of Saffron and Photobiomodulation on the light damaged rat retina.

Aim: To identify the genes and non-coding RNAs (ncRNAs) involved in the neuroprotective actions of a dietary anti-oxidant (saffron) and of photobiomodulation. Methods: We used a previously published assay of photoreceptor damage, in which albino Sprague Dawley rats raised in dim cyclic illumination ...

ORGANISM(S): Rattus norvegicus

2010-07-16 | E-GEOD-22818 | biostudies-arrayexpress

Global Metabonomic and Proteomic Analysis of Human Conjunctival Epithelial Cells (IOBA-NHC) in Response to Hyperosmotic Stress

“Dry eye” is a multi-factorial inflammatory disease affecting the ocular surface. Tear hyperosmolarity in dry eye contributes to inflammation and cell damage. Recent research efforts on dry eye have been directed towards biomarker discovery for diagnosis, response to treatment and disease mechanisms...

ORGANISM(S): Homo sapiens (Human)

2015-08-17 | PXD002661 | Pride

Metabonomics Proteomics Osmostic stress Metabolomics Swath Dry eye Hyperosmolarity Osmoprotectants Itraq

Transcriptomic Profiling of Orbital Fat Tissue and Ocular Surface Wash in Active Thyroid Eye Disease Requiring Urgent Orbital Decompression.

Not available

S-EPMC12758420 | biostudies-literature

Timed topical dexamethasone eye drops improve mitochondrial function to suppress severe retinopathy of prematurity.

Pathological neovascularization (NV) can cause visual impairment in retinopathy of prematurity (ROP). Current treatments addressing vasoproliferative (Phase II) ROP are costly and can lead to severe complications. We show that well-timed topical 0.1% dexamethasone eye drops during early retinal neov...

ORGANISM(S): Mus musculus (Mouse)

2025-05-07 | PXD052730 | Pride

Retinopathy of prematurity Steroid Oxygen-induced retinopathy Dexamethasone Eye drop

Adult zebrafish: cornea vs dermis

Transcriptional profiling of adult zebrafish cornea against dermis as a reference. Three biological repeats with dye swap (6 chips of 1x22k for 6 data sets).

ORGANISM(S): Danio rerio

2015-02-19 | E-GEOD-24593 | biostudies-arrayexpress

Assessment of eye drop instillation technique in patients with glaucoma: a hospital-based cross-sectional study in Eastern China.

Not available

S-EPMC12486826 | biostudies-literature

Adult zebrafish: cornea vs epidermis

Transcriptional profiling of adult zebrafish cornea against epidermis as a reference. Four biological repeats with dye swap (2 chips of 4x44k for 8 data sets).

ORGANISM(S): Danio rerio

2015-02-19 | E-GEOD-24595 | biostudies-arrayexpress

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