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ProteomicsProtein and Signaling Pathway Responses to rhIL-6 Intervention before Lobaplatin Treatment in Osteosarcoma Cells using LC-MS/MS
Lobaplatin is a third-generation platinum-based antineoplastic agent and is widely used for osteosarcoma treatment before and after tumor removal. However, treatment failure often results from lobaplatin drug resistance. In our study, we found that SaOS-2 and SOSP-9607 osteosarcoma cells became less...
ORGANISM(S): Homo sapiens (Human) 
2021-02-25 | PXD021564 | Pride
Human Lobaplatin Rhil-6 Osteosarcoma Liquid chromatography-tandem mass spectrometry 
ProteomicsProteomics-based identification of potential therapeutic targets of artesunate in a lupus nephritis MRL/lpr mouse model
A total of 6527.0 proteins were identified in the First Affiliated Hospital of Sun Yat sen University, of which 5732.0 proteins contained quantitative information. If we take 1.5 times as the differential expression change threshold and t-test p-value < 0.05 as the significance threshold, we found t...
ORGANISM(S): Mus musculus (Mouse) 
2024-05-24 | PXD046815 | Pride
Lupus nephritis artesunate tmt-based quantitative proteomics 
ProteomicsConotoxin Exploitation from Conus betulinus
Employing Conus betulinus as a representative, we sequenced and assembled the first Conus genome. After integration of multi-omics data, we provide novel insights into the genetic central dogma of conotoxins, assuming a number ratio of ~1:1:10s for genes/transcripts/peptides.
ORGANISM(S): conus betulinus 
2021-09-08 | PXD014892 | Pride
Conus  genome  conotoxins  multi-omics  transcript  proteomics  peptide 
MultiomicsA549 cells -- High-throughput Secretomic Analysis of Single Cells
High-throughput secretomic analysis of single A549 cells.
2015-10-06 | LDS-1107 | LINCS
MultiomicsU87 cells -- High-throughput Secretomic Analysis of Single Cells
High-throughput secretomic analysis of single U87 cells.
2015-10-06 | LDS-1108 | LINCS
MultiomicsU937 cells -- High-throughput Secretomic Analysis of Single Cells
High-throughput secretomic analysis of single U937 cells.
2015-10-06 | LDS-1109 | LINCS
TranscriptomicsIdentification of Rhizome-Specific Genes by Genome-wide Differential Expression Analysis in Oryza longistaminata
The Oryza longistaminata is a perennial wild rice species with AA genome, which characterized by the presence of rhizomatous stem. The rhizomatousness trait in rice was previously identified quantitatively controlled by many genes, but the molecular mechanism related to the rhizome initiation and el...
ORGANISM(S): Oryza longistaminata 
2010-10-31 | E-GEOD-24228 | biostudies-arrayexpress
ProteomicsThe protein binding with diabetes induced circulation associated circular RNA of db/db mouse heart detected by label free LC-MSMS
The protein binding with diabetes induced circulation associated circular RNA (DICAR) pf db/db mouse compared with wild type
ORGANISM(S): Mus Musculus 
2022-10-27 | PXD037745 |
ProteomicsNovel Molecular Subgroups of Intrahepatic Cholangiocarcinoma Discovered by Single-Cell RNA Sequencing-Assisted Multi-Omics Analysis
Intrahepatic cholangiocarcinoma (ICC) is a relatively rare but highly aggressive tumour type that responds poorly to chemotherapy and immunotherapy. Comprehensive molecular characterization of ICC is essential for the development of novel therapeutics. Here, we constructed two independent cohorts fr...
ORGANISM(S): Homo Sapiens 
2022-04-13 | PXD033206 |
ProteomicsiTRAQ-based proteomic analysis of Deinococcus radiodurans in response to 12C6+ heavy ions irradiation
Proteome of Deinococcus radiodurans which were treaded by four different doses of heavy ion radiation.
ORGANISM(S): Deinococcus Radiodurans R1 
2022-02-28 | PXD031902 |
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