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TranscriptomicsCopper-regulated genes of Bradyrhizobium japonicum
Copper-limiting growth conditions were thought to cause an induction of genes possibly involved in copper uptake and sorting. This rationale in mind, we performed microarray analyses on B. japonicum cells grown in three variations of the BVM minimal medium. Variant 1 contained 2 M-NM-
ORGANISM(S): Bradyrhizobium japonicum 
2012-10-01 | E-GEOD-40437 | biostudies-arrayexpress
MetabolomicsUrine metabolomic profiling in two siblings with biallelic pathogenic ATG7 variants with healthy control
Ultra-rare biallelic ATG7 variants were recently reported in five families presenting with neurodevelopmental disorders. Two adult female siblings (P1 and P2) from one family carried compound heterozygous loss-of-function variants (c.1975C>T [p.Arg659]; c.2080-2A>G, 39,40NM_006395.2), resulting in u...
2026-09-30 | MTBLS15856 | MetaboLights
UnknownHigh vaccination coverage and infection rate result in a robust SARS-CoV-2-specific immunity in the majority of liver cirrhosis and transplant patients: A single-center cross-sectional study.
Not available
S-EPMC11017769 | biostudies-literature
TranscriptomicsTranscriptomic effects of endocrine disruptors in zebrafish embryos
The identification of endocrine disruptive properties of chemicals certain to enter the aquatic environment relies on toxicity tests with fish, assessing adverse effects on reproduction and sexual development. The demand for quick, reliable endocrine disruption (ED) assays favored the use of fish em...
ORGANISM(S): Danio rerio 
2014-03-06 | E-GEOD-44263 | biostudies-arrayexpress
TranscriptomicsMYCN and HDAC2 cooperate to repress miR-183 signaling in neuroblastoma.
MYCN is a master regulator controlling many processes necessary for tumor cell survival. Here, we unravel a microRNA network that causes tumor suppressive effects in MYCN-amplified neuroblastoma cells. In profiling studies, histone deacetylase (HDAC) inhibitor treatment most strongly induced miR-183...
ORGANISM(S): Homo sapiens 
2013-05-01 | E-GEOD-44538 | biostudies-arrayexpress
ProteomicsProteome profiling of blood plasma-derived exosomes in chronic lymphocytic leukemia
In order to analyze differences in the proteome composition of blood plasma-derived exosomes in chronic lymphocytic leukemia (CLL) versus healthy donors, mass spectrometry was conducted for whole protein lysates of plasma-derived exosomes. Abundance of proteins was compared via label free quantifica...
ORGANISM(S): Homo sapiens (Human) 
2017-08-09 | PXD004420 | Pride
Extracellular vesicles Microvesicles Mass spectrometry Maxquant Cll Tumor microenvironment Chronic lymphocytic leukemia 
OtherThe Proteome of the Isolated Chlamydia trachomatis Containing Vacuole Reveals a Complex Trafficking Platform Enriched for Retromer Components.
Data from ProteomeXchange, PXD ID: PXD002113. File: 130514_LA_C_92_SAX8.mzml. Published as part of PLoS Pathog. 2015 Jun 4;11(6):e1004883 . From the Abstract: {{i}} Chlamydia trachomatis is an important human pathogen that replicates inside the infected host cell in a unique vacuole, the inclusion....
ORGANISM(S): Homo_sapiens_viruses, Human_female, Chlamydia_trachomatis_l2b_uch_1_proctitis, Chlamydia_trachomatis_l2c 
GPM32310020401 | GPMDB
Resource Reanalysis 
ProteomicsMapping of ISG15 interaction partners by Virotrap coupled to mass spectrometry
During infection, interferon production leads to upregulation of the interferon-stimulated gene 15 (ISG15) which encodes the ubiquitin-like protein ISG15. ISG15 has a profound role in restricting intracellular infection by viral and bacterial pathogens. It can exert its function either as a free int...
ORGANISM(S): Homo sapiens (Human) 
2021-08-16 | PXD018345 | Pride
Isg15 Virotrap Human Interactome 
TranscriptomicsGene expression in striatums of Foxp2-hum, Foxp2-ko and wild-type mice
It has been proposed that two amino acid substitutions in the transcription factor FOXP2 have been positively selected during human evolution due to effects on aspects of speech and language. Here, we introduce these substitutions into the endogenous Foxp2 gene.of mice. Although these mice are gener...
ORGANISM(S): Mus musculus 
2010-05-22 | E-GEOD-13588 | biostudies-arrayexpress
UnknownRivaroxaban or aspirin for patent foramen ovale and embolic stroke of undetermined source: a prespecified subgroup analysis from the NAVIGATE ESUS trial.
Not available
S-EPMC6662613 | biostudies-literature
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