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ProteomicsThermal proteome profilling of Ergothionine treated-cells reveals its binding to cystathionine-gamma-lyase (CSE)
Ergothioneine (ET), a dietary thione/thiol, is receiving growing attention for its possible benefits in healthy aging and metabolic resilience. Our study investigates ET's effects on healthspan in aged animals, revealing extension of lifespan and enhanced mobility in Caenorhabditis elegans, accompan...
ORGANISM(S): Mus musculus (Mouse) 
2025-01-20 | PXD051609 | Pride
Ergothioneine Healthspan Persulfidation Hydrogen sulfide Nad 
TranscriptomicsTranscription profiling of hyperthermophilic crenarchaeum Thermoproteus tenax to compare autotrophic growth on CO2/H2 versus heterotrophic growth on glucose using a focussed central carbohydrate metabolism DNA microarray
In order to unravel the role of regulation on transcript level in the central carbohydrate metabolism (CCM) of Thermoproteus tenax (glycolytic/gluconeogenic carbon switch), the focused DNA microarray was constructed by using ORFs supposed to be involved in the CCM pathways. Transcriptional profiling...
ORGANISM(S): Thermoproteus tenax 
2008-02-05 | E-MEXP-1376 | biostudies-arrayexpress
ProteomicsIdentification of protein-trichloroethene interactions during organohalide respiration revealed by thermal proteome profiling
The organohalide-respiring Sulfurospirillum multivorans uses chlorinated ethenes as electron acceptors for growth under anoxic conditions. However, little is known about the interaction of these substrates with proteins. Here, we apply thermal proteome profiling (TPP) to analyze enzyme-trichloroethe...
ORGANISM(S): Sulfurospirillum multivorans DSM 12446 
2018-06-06 | PXD009308 | Pride
Thermal proteome profiling (tpp)  interaction proteome  organohalide respiration  reductive dehalogenases  sulfurospirillum multivorans  dehalococcoides mccartyi  quantitative proteomics 
UnknownGender- and sex-sensitive psychopharmacotherapy of alcohol use disorder: a systematic review and meta-analysis protocol.
Not available
S-EPMC12682176 | biostudies-literature
UnknownAquaporin tetramer composition modifies the function of tobacco aquaporins.
Not available
S-EPMC2951199 | biostudies-literature
TranscriptomicsTelomerase is a prognostic marker of poor outcome and a therapeutic target in neuroblastoma
The aim of this study is to determine the clinical relevance of telomerase activation versus ALT as biomarkers in pre-treatment neuroblastoma, and to assess the potential value of telomerase as a therapeutic target. Therefore, the genomic status of TERT and MYCN was assessed in 457 pretreatment neur...
ORGANISM(S): Homo sapiens 
2019-09-16 | E-MTAB-8248 | biostudies-arrayexpress
GenomicsDAC University Hospital Cologne
Data Access Committee EGAC00001000361
EGAC00001000361 | EGA
TranscriptomicsGene expression in striatums of Foxp2-hum, Foxp2-ko and wild-type mice
It has been proposed that two amino acid substitutions in the transcription factor FOXP2 have been positively selected during human evolution due to effects on aspects of speech and language. Here, we introduce these substitutions into the endogenous Foxp2 gene.of mice. Although these mice are gener...
ORGANISM(S): Mus musculus 
2010-05-22 | E-GEOD-13588 | biostudies-arrayexpress
UnknownThe interplay of family history of depression and early trauma: associations with lifetime and current depression in the German national cohort (NAKO).
Not available
S-EPMC10959537 | biostudies-literature
Genomicsena-DATASET-UCL-ICH-25-11-2015-12:32:35:398-26 - samples
Description not provided
EGAD00001001687 | EGA
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