Sort   by:  
 Page size 
TranscriptomicsEffects of retene, pyrene and phenanthrene on the cardiac transcriptome of the rainbow trout larva
This study explores the mechanisms of cardiotoxicity of the three widespread model polycyclic aromatic hydrocarbons retene, pyrene and phenanthrene in the rainbow trout (Oncorhyncus mykiss) early life stages. Newly hatched larvae were exposed to each individual compound at sublethal doses: DMSO (con...
ORGANISM(S): Oncorhynchus mykiss 
2020-07-29 | E-MTAB-8750 | biostudies-arrayexpress
TranscriptomicsRNA-seq of Cryptomonas sp. under phototrophic and glucose supplemented phototrophic conditions, together with 3 dissolved organic carbon concentrations
Cryptomonas sp. was grown under phototrophic conditions, glucose supplemented phototrophic conditions and 3 different dissolved organic carbon (DOC) concentrations: 1.5, 30 and 90 mg C l−1. The objective was to study the adaptations that make Cryptomonas sp. thrive under high DOC conditions.
ORGANISM(S): Cryptomonas sp. CPCC 336 
2022-07-12 | E-MTAB-11370 | biostudies-arrayexpress
ProteomicsIdentification of proteins in SDS-PAGE gel by LC-MSMS
Recombinant antibodies were purified from culture supernatants derived from the Dictyostelium discoideum model and loaded into an SDS-PAGE electrophoresis gel. The electrophoretic profile of the anti-alpha tubulin, anti-CISD1, and anti-CD8β antibodies reveals a band at 35 kDa, likely corresponding t...
ORGANISM(S): Dictyostelium discoideum (Slime mold) 
2025-04-11 | PXD053343 | Pride
Dictyostelium discoideum Recombinant antibodies 
GenomicsWhole genome sequencing of spontaneous resistant mutants of Mycobacterium tuberculosis H37Rv selectec in the presence of BVL3572S and amino acids
M. tuberculosis H37Rv cultures were exposed to BVL3572S in the absence or presence of L-histidine or L-alanine for at least 4 weeks. Individual colonies were picked and their genomic DNA extracted, indexed, and sequenced.
ORGANISM(S): Mycobacterium tuberculosis 
2026-06-03 | E-MTAB-17255 | biostudies-arrayexpress
MetabolomicsDifferential role of sphingomyelin in influenza virus, rhinovirus and SARS-CoV-2 infection of Calu-3 cells
Host cell lipids play a pivotal role in the pathogenesis of respiratory virus infection. However, a direct comparison of the lipidomic profile of influenza virus and rhinovirus infections is lacking. In this study, we first compared the lipid profile of influenza virus and rhinovirus infection in a ...
2022-11-15 | MTBLS2352 | MetaboLights
UnknownAdjuvant Gemcitabine Plus Docetaxel Followed by Doxorubicin Versus Observation for High-Grade Uterine Leiomyosarcoma: A Phase III NRG Oncology/Gynecologic Oncology Group Study.
Not available
S-EPMC6241678 | biostudies-literature
MetabolomicsDeep longitudinal multi-omics analysis of Bordetella pertussis cultivated in bioreactors highlights medium starvations and transitory metabolisms, associated to vaccine antigen biosynthesis variations and global virulence regulation

Bordetella pertussis is the bacterial causative agent of whooping cough, a serious respiratory illness. An extensive knowledge on its virulence regulation and metabolism is a key factor to ensure pertussis vaccine manufacturing process robustness. The aim of this study was to refine our ...

2023-02-21 | MTBLS5762 | MetaboLights
ProteomicsMulti-omics analysis of Bordetella pertussis fermentation
Bordetella pertussis is the bacterial causative agent of whooping cough, a serious respiratory illness. An extensive knowledge on its virulence regulation and metabolism is a key factor to ensure pertussis vaccine manufacturing process robustness. The aim of this study was to refine our comprehensio...
ORGANISM(S): Bacteria Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251) 
2023-03-11 | PXD039615 | Pride
Longitudinal multi-omics Virulence Fermentation molecular profiling Antigen production Proline starvation Bordetella pertussis Bacterial fermentation Cysteine starvation 
ProteomicsIdentification of bacteriolytic lysosomal proteins in Dictyostelium discoideum by LC-MSMS
In order to identify new D. discoideum proteins involved in the intracellular destruction of ingested bacteria, the amoeba cell lysate was fractionated, and the obtained fractions were screened for their bacteriolytic activity. The few fractions presenting a bacteriolytic activity were analyzed by m...
ORGANISM(S): Dictyostelium discoideum (Slime mold) 
2021-01-20 | PXD020632 | Pride
Lc-msms Dictyostelium Lysosomal proteins 
ProteomicsEffects of retene, pyrene and phenanthrene on the cardiac proteome of the rainbow trout larva
The mechanisms of cardiotoxicity of the three widespread model polycyclic aromatic hydrocarbons (PAHs) retene, pyrene and phenanthrene were explored in rainbow trout (Oncorhyncus mykiss) early life stages. Newly hatched larvae were exposed to sublethal doses of each individual PAH causing no detecta...
ORGANISM(S): Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri) 
2020-08-06 | PXD017294 | Pride
Cardiotoxicity Proteomics Metabolomics Polycyclic aromatic hydrocarbons (pahs) Aquatic toxicology Developmental toxicity 
Sort   by:  
 Page size