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ProteomicsTowards comprehensive plasma proteomics by orthogonal protease digestion
Rapid and consistent protein identification across large clinical cohorts is an important goal for clinical proteomics. With the development of data-independent technologies (DIA/SWATH-MS), it is now possible to analyze hundreds of samples with great reproducibility and quantitative accuracy. Howev...
ORGANISM(S): Mycobacterium tuberculosis TKK-01-0032 Homo sapiens (Human) 
2021-07-29 | PXD025671 | Pride
Human Dia-ms Clinical proteomics Tb 
ProteomicsMechanotransduction coordinates extracellular matrix protein homeostasis promoting longevity in C. elegans
Although it is postulated that dysfunctional extracellular matrices (ECM) drive aging and disease, how ECM integrity assures longevity is unknown. Here, using proteomics and in-vivo monitoring of fluorescently tagged ECM proteins, we systematically examined the ECM composition during Caenorhabditis ...
ORGANISM(S): Caenorhabditis elegans 
2023-11-16 | PXD046470 | Pride
Dia 
ProteomicsAnalalysis of ASB6-UBA3-NAE1 interaction
Validation of ASB6 and NAE1-UBA3 interaction using SH tagged cell lines
ORGANISM(S): Homo sapiens (Human) 
2021-01-29 | PXD022175 | Pride
Asb6 pulldown Dda and prm 
ProteomicsSARS-CoV-2 variants of concern have acquired mutations associated with an increased spike cleavage
Quantification of Spike cleavage across different Sars-Cov2 variants by partial reaction monitoring mass spectrometry
ORGANISM(S): Homo sapiens (Human) 
2022-02-22 | PXD027641 | Pride
Furin Gluc Sars-cov2 Prm 
ProteomicsIn Vivo Protein Turnover Rates in Varying Oxygen Tensions Nominate MYBBP1A as a Novel Mediator of the Hyperoxia Response
Oxygen deprivation and excess are both toxic to mammals. Thus, the ability to adapt to varying oxygen tensions is critical for survival. While the transcriptional response to acute hypoxia has been well-studied, the post-translational effects of hypoxia and hyperoxia have been underexplored. In this...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2023-06-04 | MSV000092095 | MassIVE
UnknownObesity is associated with shorter telomeres in 8 year-old children.
Not available
S-EPMC6904465 | biostudies-literature
TranscriptomicsRNA-seq time-course of Calu-3 cells infected with SARS-CoV-2 early-lineage and Alpha variant viruses
Emergence of SARS-CoV-2 variants of concern (VOCs), including the globally successful Alpha (B.1.1.7) variant, suggests viral adaptation to enhance human-to-human transmission. Although much effort has focused on characterisation of spike changes, Alpha mutations outside spike likely contribute to a...
ORGANISM(S): Homo sapiens 
2021-12-31 | E-MTAB-11275 | biostudies-arrayexpress
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