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Guanine quadruplexes (G4s) are unique secondary structures of nucleic acids with functions in many biological processes. Understanding the biological functions of DNA G4s requires the knowledge about their recognitions by cellular proteins. Affinity pull-down coupled with LC-MS/MS analysis was previ...
ORGANISM(S): Homo sapiens (Human) 
2026-02-02 | PXD051342 | Pride
DNA sequences of high guanine (G) content have the potential to fold into G quadruplex (G4) structures. DNA G4 is known to play important roles in various cellular processes including DNA replication, transcriptional regulation, and maintenance of genomic integrity. A more complete understanding abo...
ORGANISM(S): Homo sapiens (Human) 
2021-09-29 | PXD026794 | Pride
Radiotherapy benefits more than 50% of cancer patients and cures 40% of them, where ionizing radiation deposits energy to cells and tissues, thereby eliciting DNA damage and resulting in cell death. Small GTPases are a superfamily of proteins that play critical roles in cell signaling. Several small...
ORGANISM(S): Homo sapiens (Human) 
2024-01-26 | PXD034360 | Pride
Proteomic analysis on the underlying mechanisms of PoTX-induced nerve injury
ORGANISM(S): Homo sapiens (Human) 
2025-07-21 | PXD060121 | Pride
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