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Alternative splicing is a tightly regulated process essential for transcriptomic and proteomic diversity, and its dysregulation has been implicated in various cancers. Ubiquitin-specific protease 39 (USP39) is a core component of the spliceosome that lacks enzymatic activity, rendering it challengin...
ORGANISM(S): Homo sapiens (Human) 
2026-02-09 | PXD065738 | Pride
Lung cancer cells rely on protein homeostasis regulators, especially within the ubiquitin-proteasome system (UPS), to sustain malignancy. Genetic alterations in UPS components, such as E3 ubiquitin ligases (E3s) and deubiquitinating enzymes (DUBs), are common and create context-dependent therapeutic...
ORGANISM(S): Mus musculus (Mouse) 
2026-02-04 | PXD067472 | Pride
This SuperSeries is composed of the following subset Series: GSE35186: Paradigm Test Set Expression Array GSE35189: Paradigm Test Set aCGH Array Refer to individual Series
ORGANISM(S): Homo sapiens 
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