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ProteomicsGastric cancer ascites proteome
Gastric cancer is one of the most lethal malignancies with high mortality and gastric cancer-specific biomarker is need due to the lack of specific method for early screening, diagnosis, and prognosis of the patients with gastric cancer. Ascites is known for an important source for conducing biomark...
ORGANISM(S): Homo sapiens (Human) 
2018-04-16 | PXD002213 | Pride
Proteome profiling Proteomics Ascites Gastric cancer Biomarker 
ProteomicsHelicobacter pylori infection dysregulates gastric proteome
The purpose of the study was to define gastric cell-specific proteomic changes, induced by H. pylori oncogenic strains, that are critical for initiation of the gastric carcinogenic cascade. Gastric cell scrapings were harvested from H. pylori-infected and uninfected animals for quantitative proteomi...
ORGANISM(S): Meriones unguiculatus 
2018-11-23 | PXD009583 | Pride
Gastric proteome Helicobacter pylor 
ProteomicsIdentification of gastric cancer associated serum antibodies using Helicobacter pylori antigen microarrays
Unbiased de-novo identification of biomarkers for H.pylori associated gastric cancer; Microarrays, representing 242 seroreactive H.pylori proteins, were generated by spotting of the respective gene constructs and cell-free on-chip expression. Antibody levels to these proteins were measured by appli...
ORGANISM(S): Homo sapiens 
2020-09-14 | E-MTAB-9534 | biostudies-arrayexpress
ProteomicsPGRC Cancer Proteome Study of Gastric Tissue
The goal of the project is to analyze different layers of proteome information including protein abundance and post-translational modifications of PGRC gastric tissue samples. Three pairs of human gastric cancer and adjacent normal tissues were extensively characterized by serial enrichments of phos...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-31 | MSV000080818 | MassIVE
ProteomicsMining potential serum biomarkers for gastric adenocarcinoma using quantitative proteomics
Serum is a valuable body fluid to diagnose cancer as it can be accessed with minimal invasive techniques. Studying the cancer serum proteome provides valuable insights into the pathophysiology of tumor progression. Gastric adenocarcinoma is an aggressive cancer resulting in poor prognosis, mainly du...
ORGANISM(S): Homo sapiens (Human) 
2015-07-27 | PXD001265 | Pride
Serum biomarkers Gastric cancer Quantitative proteomics Adenocarcinoma 
ProteomicsMining gastric cancer cellular quantitative proteomics data to analyse the proteome change upon CAMKK2 inhibition
Gastric cancer is a global health concern. Molecular alterations in various signaling pathways have been implicated in the development and late-stage progression/metastasis of gastric cancer. Reports have suggested that Wnt signaling pathway might contribute to gastric carcinogenesis by stimulating ...
ORGANISM(S): Homo sapiens (Human) 
2021-04-13 | PXD023423 | Pride
Sto-609 Data mining Camkk2 Mass spectrometry Proteomics Gastric cancer 
MetabolomicsCTH exacerbates Helicobacter pylori immunopathogenesis by promoting macrophage metabolic remodeling and activation
Macrophages play a crucial role in the inflammatory response to the human stomach pathogen Helicobacter pylori, which infects half of the world's population and causes gastric cancer. Recent studies have highlighted the importance of macrophage immunometabolism in their activation state and function...
2022-06-14 | MTBLS2851 | MetaboLights
ProteomicsMining gastric cancer cellular quantitative phosphotyrosine proteomics data to analyse the signiling cascade regulated my CAMKK2 in gastric cancer
Gastric cancer is a global health concern. Tyrosine kinases (TKs) are important mediators of signaling cascades, which regulate diverse biological processes like growth, differentiation, metabolism, and apoptosis in response to external and internal stimuli. Molecular alterations in various signalin...
ORGANISM(S): Homo sapiens (Human) 
2022-06-09 | PXD032001 | Pride
Sto-609 Data mining Camkk2 Mass spectrometry Proteomics Stat3 Gastric cancer 
ProteomicsLabel-free quantitative proteomics of gastric high-grade intraepithelial neoplasia
Purpose: Early detection and diagnosis are the keys to improving the survival rate and reducing the fatality rate linked to gastric cancer. The precancerous lesion of gastric cancer is referred to as Gastric high-grade intraepithelial neoplasia (HGIN). Both sensitivity and specificity of current bio...
ORGANISM(S): Homo sapiens (Human) 
2025-06-02 | PXD036991 | Pride
Gastric cancer  gastric high-grade intraepithelial neoplasia  proteomics  label-free 
ProteomicsPhosphoproteomics and global proteomic analysis of gastric cancer cell lines
proteome, pSTY proteome and pY proteome analysis was performed using 13 gastric cancer cell lines w/wo apatinib treatment.
ORGANISM(S): Homo Sapiens (human) 
2023-11-04 | PXD037961 | JPOST Repository
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