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This dataset results from the discovery, characterization and validation of 74 genetically variant peptides from fingermark protein. These peptides contain single amino acid polymorphisms, the result of non-synonymous SNPs. Detection of these peptide markers in fingermark proteomic datasets allows i...
ORGANISM(S): Homo sapiens (Human) 
2019-06-19 | PXD012628 | Pride
Proteins of the human hair shaft contain a wealth of information about the coding regions of the person’s genome from whom the hair is derived. Commonly found at crime scenes, hair shafts may thus provide useful forensic evidence if the information they contain can be exploited. Present experiments ...
ORGANISM(S): Homo sapiens (Human) 
2019-04-04 | PXD011732 | Pride
Hair, a skin appendage, is a frequently procured biological specimen from crime scenes and has been used in forensic investigations for over a century. Proteomic analysis and identification of genetically variant peptides (GVPs) in hair samples for identification purposes is a recent but an efficien...
ORGANISM(S): Homo sapiens (Human) 
2020-06-10 | PXD016169 | Pride
Proteomic genotyping is the use of genetically variant peptides (GVPs), detected in a forensic protein sample, to infer the genotype of corresponding non-synonymous SNP alleles in the donor’s genome. This process does not depend on the presence of accessible or useable DNA in a sample. This makes pr...
ORGANISM(S): Homo sapiens (Human) 
2020-05-27 | PXD016156 | Pride
Forensic association of hair shaft evidence with individuals is currently assessed by comparing mitochondrial DNA haplotypes of reference and casework samples, primarily for exclusionary purposes. Present work tests and validates more recent proteomic approaches to extract quantitative transcription...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-10-26 | MSV000080295 | MassIVE
Recent reports highlight improved individual identification using proteomic information from human hair evidence. These reports have stimulated investigation of parameters that affect the utility of proteomic information. In addition to variables already studied relating to processing technique and ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-02-27 | MSV000085030 | MassIVE
In this study we performed proteogenomic analysis for 9 cell lines of malignant melanoma. The main objectives of the study were identifying the variants originating from point mutations and analyzing the effect of exome data filtering on the outcome of variant identification.
ORGANISM(S): Homo sapiens (Human) 
2018-12-05 | PXD007662 | Pride
Characterization of body location-specific hair proteomic variation and its effect on the identification of genetically variant peptide markers for protein-based human identification. LLNL-MI-756827
ORGANISM(S): Homo sapiens (Human) 
2019-05-22 | PXD010982 | Pride
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