The organometallic gold(I) bis-N-heterocyclic carbene complex [Au(9-methylcaffeine-8-ylidene)2]+ (AuTMX2) was previously shown to selectively and potently stabilise telomeric DNA G-quadruplex (G4) structures. This study sheds light onto the molecular reactivity and mode of action of AuTMX2 in the ce...
Primary human peripheral blood mononuclear cells were isolated from full blood by standard ficoll centrifugation. Cells were washed and processed immediately.
Human T-cells were isolated from full blood by ficoll centrifugation and subsequent negative depletion with magnetic beads of monocytes and B-cells and treated with 5ug/ml PHA for 24 hours.
Gendered burial practices that differentiate between men and women by the way the body was placed were used over large parts of Central Europe in the Late Neolithic and Early Bronze Age (c. 2900−1600 BC). The differentiation of bodies placed on the left/right side in opposite orientation was extende...
