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UnknownBisphenol A Regulates Sodium Ramp Currents in Mouse Dorsal Root Ganglion Neurons and Increases Nociception.
Not available
S-EPMC6635372 | biostudies-literature
UnknownGenomic Validation of Endometrial Cancer Patient-Derived Xenograft Models as a Preclinical Tool.
Not available
S-EPMC9181722 | biostudies-literature
TranscriptomicsThe cellular origin and malignant transformation of Waldenström's Macroglobulinemia [copy number variation]
Although information on the molecular pathogenesis of Waldenström’s Macroglobulinemia (WM) has greatly improved in recent years, the exact cellular origin and the mechanisms behind WM transformation from IgM MGUS remain undetermined. Here, we undertook an integrative phenotypic, molecular and genomi...
ORGANISM(S): Homo sapiens 
2015-05-06 | E-GEOD-61650 | biostudies-arrayexpress
UnknownThe Nutritional Status of Long-Term Institutionalized Older Adults Is Associated with Functional Status, Physical Performance and Activity, and Frailty.
Not available
S-EPMC8619061 | biostudies-literature
ProteomicsProteomic workflows for high quality quantitative proteome and PTM analysis of clinically relevant samples from FFPE archives
Well-characterized archival FFPE tissues are of much value for prospective biomarker discovery studies. Protocols that offer high-throughput and good reproducibility are essential in proteomics. Therefore, we developed a workflow implementing efficient paraffin removal and protein extraction from FF...
ORGANISM(S): Homo sapiens (Human) 
2020-12-18 | PXD021986 | Pride
Cancer Lung adenocarcinoma Suspension trapping (s-trap) Lysine acetylation stoichiometry Mass spectrometry Clinical proteomics Ffpe tissue Sample preparation High-throughput Isobaric labeling (tmt) 
ProteomicsProteomic workflows for high quality quantitative proteome and PTM analysis of clinically relevant samples from FFPE archives
Well-characterized archival FFPE tissues are of much value for prospective biomarker discovery studies. Protocols that offer high-throughput and good reproducibility are essential in proteomics. Therefore, we developed a workflow implementing efficient paraffin removal and protein extraction from FF...
ORGANISM(S): Homo sapiens (Human) 
2020-12-18 | PXD021964 | Pride
Cancer Lung adenocarcinoma Suspension trapping (s-trap) Lysine acetylation stoichiometry Mass spectrometry Clinical proteomics Ffpe tissue Sample preparation High-throughput Isobaric labeling (tmt) 
ProteomicsClinical proteomics workflow for high quality quantitative proteome and PTM analysis of biologically relevant FFPE tissue samples
In recent years, the use of formalin-fixed paraffin-embedded (FFPE) tissues has increased within cancer research and clinical proteomics. However, the use of FFPE tissues can be demanding due to paraffin embedding and cross-links introduced by the formaldehyde. Here, we developed a workflow implemen...
ORGANISM(S): Homo sapiens (Human) 
2020-12-18 | PXD020157 | Pride
Cancer Suspension trapping Lung adenocarcinoma Mass spectrometry Clinical proteomics Lysine acetylation stoichiomtery Throughput Proteomics Tissue Isobaric labeling Tmt Ffpe Sample preparation S-trap 
TranscriptomicsRNA-Seq analysis of transcriptomes of B. amyloliquefaciens FZB42 in biofilm formation and planktonic cells.
This experiment compares the transcriptomes of B. amyloliquefaciens FZB42 cells in biofilm formation and in planktonic cells focusing on transcripts that were most affected in their transcription. The aim of the experiment was determination of the highest expressed genes in both cultures using RPKM ...
ORGANISM(S): Bacillus amyloliquefaciens 
2017-03-16 | E-MTAB-4362 | biostudies-arrayexpress
ProteomicsKChIP3 promotes Alzheimer´s disease by impairing long-term potentiation and memory
Alzheimer's disease (AD) is a multifactorial disorder with serious social, health, and economic implications, affecting over 30 million individuals worldwide, and this number may triple by the year 2050. To date, there are no accurate biomarkers for early diagnosis nor effective treatments to delay ...
ORGANISM(S): Mus musculus (Mouse) 
2025-06-30 | PXD054699 | Pride
Neuroinflammation Kchip3 Alzheimer´s disease 
ProteomicsProteogenomics linked to histopathology identifies subtypes and progression biomarkers in malignant melanoma
In this study, proteogenomic analysis coupled with clinical histopathology revealed proteomic subtypes and identified candidate markers, which uncovered tumor biology related to patient survival. A total of 12,695 proteins and 45,356 phosphosites were quantified. This newly generated proteomic data ...
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD035206 | Pride
Cancer Proteomics Mass spectrometry Melanoma Proteogenomics Metastasis 
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