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Proteomicsmembrane substrates of gingipains
Porphyromonas gingivalis secretes cysteine proteases named gingipains which can cleave an array of proteins and importantly contribute to the development of periodontitis. In this study we focused on gingipain-exerted proteolysis at the cell surface of human gingival epithelial cells (telomerase imm...
ORGANISM(S): Homo sapiens (Human) 
2020-04-28 | PXD015679 | Pride
Protease Shedding Gingipain Anoikis Proteolysis 
ProteomicsGingipain transpeptidation - Porphyromonas gingivalis Gingipains Display Transpeptidation Activity
Porphyromonas gingivalis is a keystone periodontal pathogen that has been associated with autoimmune disorders. The cell surface proteases Lys-gingipain (Kgp) and Arg-gingipains (RgpA and RgpB) are major virulence factors and their proteolytic activity is enhanced by small peptides such as glycylgly...
ORGANISM(S): Homo sapiens (Human) 
2018-07-11 | PXD009950 | Pride
Transpeptidation Hemoglobin Gingipains Porphyromonas gingivalis 
GenomicsThe influence of gingipains on latent capacity of B cells
The influence of gingipains on latent capacity of B cells
PRJNA801864 | ENA
TranscriptomicsThe influence of gingipains on latent capacity of B cells
Porphyromonas gingivalis (P. gingivalis) is a key pathogen in periodontitis. Our previous study indicated that periodontitis induced by P. gingivalis increases the percentage of CD19+ B cells, Th17, Treg, gMDSCs and mMDSCs but decreases the ratio of B10 cells in CIA mice. It’s unclear which virulenc...
ORGANISM(S): Mus musculus 
2023-05-29 | GSE195704 | GEO
UnknownGingipains from Porphyromonas gingivalis - Complex domain structures confer diverse functions.
Not available
S-EPMC3894813 | biostudies-literature
UnknownLipoprotein modifications by gingipains of Porphyromonas gingivalis.
Not available
S-EPMC5969291 | biostudies-literature
UnknownUltrastructural localization of Porphyromonas gingivalis gingipains in the substantia nigra of Parkinson's disease brains.
Not available
S-EPMC11045759 | biostudies-literature
UnknownGingipains protect Porphyromonas gingivalis from macrophage-mediated phagocytic clearance.
Not available
S-EPMC11801703 | biostudies-literature
UnknownArginine-specific gingipains (RgpA/RgpB) knockdown modulates neutrophil machinery.
Not available
S-EPMC11234918 | biostudies-literature
UnknownInhibition of gingipains and Porphyromonas gingivalis growth and biofilm formation by prenyl flavonoids.
Not available
S-EPMC5199630 | biostudies-literature
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