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The objective of the experiment was to compare the proteomic profile of extracellular vesicles released by breast cancer cells in basal untreated condition (C1, C2, etc) or treated with the adipokine leptin (L1, L2 etc).
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD037266 | Pride
In this study, we employed proteomic analysis to gain deeper insights into the role of EVs in breast adiponcosis, providing novel evidence on the role of adipocyte-derived EVs in sustaining mitochondrial metabolism in breast cancer cells.
ORGANISM(S): Homo sapiens (Human) 
2025-10-27 | PXD059789 | Pride
Overcoming endocrine-resistance is the major challenge in treating Estrogen receptor (ER)-positive breast cancer. Breast Cancer Stem Cells (BCSCs) are blamed to be the driving force behind poor clinical outcomes and therapeutic resistance. Tumor microenvironment (TME) exerts a selective pressure on ...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD059964 | Pride
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