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ProteomicsHoney bee heat-shock proteomics
Honey bee colonies were maintained in an apiary at the University of British Columbia. During the summer of 2018, 40 queens were reared from a single colony and half were allowed to open mate, while the other half were kept as virgins in plastic queen cages. Two weeks after emergence, the virgin que...
ORGANISM(S): Apis mellifera (Honeybee) 
2019-07-19 | PXD013728 | Pride
Honey bee Queen Spermatheca Drone Semen Ovary 
ProteomicsA Parallel Accumulation-Mobility Aligned Fragmentation Strategy Utilizing High-Resolution Ion Mobility for High Performance Proteomics Analysis: Bulk HeLa Data Sets for PAMAF, pDIA-PAMAF, and DDA Modes
Here we present a novel data independent acquisition mass spectrometry operating mode termed parallel accumulation-mobility aligned fragmentation (PAMAF) that offers enhanced speed and sensitivity for ion fragmentation analysis for nontargeted discovery workflows such as bottom-up proteomics. This m...
ORGANISM(S): Homo sapiens (Human) 
2026-07-11 | PXD069730 | Pride
Human Pamaf Ion mobility Qtof Slim Hela Hrim Bottom-up proteomics 
ProteomicsA Parallel Accumulation-Mobility Aligned Fragmentation Strategy Utilizing High-Resolution Ion Mobility for High Performance Proteomics Analysis: HYE Quantification Data Sets for PAMAF Mode
Here we present a parallel accumulation-mobility aligned fragmentation (PAMAF) mode that expands the capabilities of the MOBILion Systems MOBIE® high-resolution ion mobility (HRIM) system for mass spectrometry-based proteomics. The MOBIE system leverages structures for lossless ion manipulation (SLI...
ORGANISM(S): Homo sapiens (Human) Escherichia coli Saccharomyces cerevisiae (Baker's yeast) 
2026-07-11 | PXD078350 | Pride
Pamaf Ion mobility Qtof Slim Hye E. coli Yeast Hela Hrim Bottom-up proteomics 
ProteomicsA Parallel Accumulation-Mobility Aligned Fragmentation Strategy Utilizing High-Resolution Ion Mobility for High Performance Proteomics Analysis: Low-Load HeLa Data Sets for PAMAF and DDA Modes
Here we present a parallel accumulation-mobility aligned fragmentation (PAMAF) mode that expands the capabilities of the MOBILion Systems MOBIE® high-resolution ion mobility (HRIM) system for mass spectrometry-based proteomics. The MOBIE system leverages structures for lossless ion manipulation (SL...
ORGANISM(S): Homo sapiens (Human) 
2026-07-11 | PXD069951 | Pride
Human Pamaf Ion mobility Qtof Slim Hela Hrim Bottom-up proteomics 
ProteomicsDevelopment of Automated Proteomic Workflows Utilizing Silicon-Based Coupling Agents
This work highlights an automated method for enzyme immobilization via 4-triethoxysilylbutyraldehyde (TESB) and 11-triethoxysilylundecanal (TESU) derived silicone-based coupling agents. From the various coupling strategies we scrutinized, TESB and 4-triethoxysilylbutanoic acid (TESBA), the carboxyli...
ORGANISM(S): Homo sapiens (Human) 
2024-06-10 | PXD051564 | Pride
Capillary electrophoresis Immobilized enzyme particle Peptide mapping Immobilized enzyme microreactor Automated liquid handler Liquid-chromatography mass spectrometry Bottom-up proteomics 
ProteomicsVirulence factors produced by Staphylococcus aureus biofilms have a moonlighting function contributing to biofilm integrity
We comprehensively profiled intracellular and ECM proteomes of S. aureus flow biofilms and complemented these data by metabolic footprint analysis and phenotypic assays. We show that S. aureus biofilms produce high amounts of secreted, moonlighting virulence factors stabilizing the ECM. Mechanistica...
ORGANISM(S): Staphylococcus aureus subsp. aureus NCTC 8325 
2019-03-13 | PXD011157 | Pride
Ecm Biofilm Staphylococcus aureus 
ProteomicsDevelopment of an Automated, Ultra-Rapid Bottom-Up Proteomics Workflow Utilizing Alginate-Based Hydrogels
A new approach to sample preparation and enzymatic digestion in bottom-up proteomics has been developed using alginate-based hydrogel entrapment of enzymes. This hydrogel facilitates rapid and room-temperature digestions with multienzyme capabilities. Three methodologies were tested: within microcen...
ORGANISM(S): Homo sapiens (Human) 
2024-11-12 | PXD052369 | Pride
Capillary electrophoresis Enzyme encapsulation Alginate Multi-enzyme digestion Hydrogel Bottom-up proteomics 
UnknownGenetic modulation of lipid profiles following lifestyle modification or metformin treatment: the Diabetes Prevention Program.
Not available
S-EPMC3431328 | biostudies-literature
UnknownSociodemographic, Clinical, and Psychosocial Predictors of Short- and Long-term Study Retention in the Diabetes Prevention Program (DPP) Outcomes Study (DPPOS).
Not available
S-EPMC12451849 | biostudies-literature
UnknownEffects of genetic variants previously associated with fasting glucose and insulin in the Diabetes Prevention Program.
Not available
S-EPMC3439414 | biostudies-literature
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