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ProteomicsFerlins and TgDOC2 in Toxoplasma microneme, rhoptry and dense granule secretion
Stable Isotope Labeling with Amino acids in Cell culture (SILAC) proteomics on the proteinsreleased in a set of T. gondii secretion mutants.
ORGANISM(S): Toxoplasma gondii CtCo5 
2021-09-10 | PXD024210 | Pride
Secretion Toxoplasma gondii 
ProteomicsPhosphoproteomic analysis of CD2 signaling reveals an AMPK-dependent targeted granule secretion in human cytotoxic T cells
The in-depth analysis of co-stimulatory signaling enhancing the activity of cytotoxic T cells represents a major approach towards the development of immunotherapies. Here we describe that CD2 co-stimulation plays a critical role in the functioning of human cytotoxic T cells (CTLs). We found that CD2...
ORGANISM(S): Homo sapiens (Human) 
2020-04-28 | PXD013840 | Pride
Cd2 Phosphoproteome Granule secretion 
TranscriptomicsPaneth cell granule dissolution and bacterial colonization in the intestine of CF mice
Paneth cells of intestinal crypts contribute to host defense by producing antimicrobial peptides that are packaged as granules for secretion into the crypt lumen. Here, we provide evidence using light and electron microscopy that postsecretory Paneth cell granules undergo limited dissolution and acc...
ORGANISM(S): Mus musculus 
2010-06-09 | E-GEOD-2958 | biostudies-arrayexpress
ProteomicsMass spectrometry analysis of the neutrophil secretome (Gelatinase/Specific granules)
Mass spectrometry analysis of the secretome of wild-type and Wash-cKO Washc1haemo) neutrophils treated with fMLF that favors Gelatinase/Specific granule secretion over azurophilic granule secretion.
ORGANISM(S): Mus musculus (Mouse) 
2022-10-13 | PXD036270 | Pride
Exocytosis Secretion Gelatinase granule Neutrophil 
UnknownSyntaxin 8 regulates platelet dense granule secretion, aggregation, and thrombus stability.
Not available
S-EPMC4340400 | biostudies-literature
UnknownDense granule biogenesis, secretion, and function in Toxoplasma gondii.
Not available
S-EPMC9482668 | biostudies-literature
TranscriptomicsMiRNA expression profiling in bone-marrow-derived neutrophils of lcn2 deficient mouse
Lipocalin 24p3 (24p3) is a neutrophil secondary granule protein. 24p3 is also a siderocalin, which binds several bacterial siderophores. It was therefore proposed that synthesis and secretion of 24p3 by stimulated macrophages or release of 24p3 upon neutrophil degranulation sequesters iron-laden sid...
ORGANISM(S): Mus musculus 
2013-01-31 | E-GEOD-43890 | biostudies-arrayexpress
TranscriptomicsGene expression profiling in bone-marrow-derived neutrophils of lcn2 deficient mouse
Lipocalin 24p3 (24p3) is a neutrophil secondary granule protein. 24p3 is also a siderocalin, which binds several bacterial siderophores. It was therefore proposed that synthesis and secretion of 24p3 by stimulated macrophages or release of 24p3 upon neutrophil degranulation sequesters iron-laden sid...
ORGANISM(S): Mus musculus 
2013-01-31 | E-GEOD-43889 | biostudies-arrayexpress
UnknownAllergen protease-activated stress granule assembly and gasdermin D fragmentation control interleukin-33 secretion.
Not available
S-EPMC11345751 | biostudies-literature
UnknownPKCalpha regulates platelet granule secretion and thrombus formation in mice.
Not available
S-EPMC2631290 | biostudies-literature
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