Sort   by:  
 Page size 
ProteomicsHuman liver cell line LO2 LC-MS/MS
A hyperlipidaemia model of L02 cells was established using free fatty acids (FFA, oleate and palmitate, 2:1; Sigma-Aldrich, USA) at a final concentration of 1 mM for 24 h. Cells were allowed to attach overnight prior to HTG-medicated serum for 24 h and then exposed to FFA during drug treatment. Afte...
ORGANISM(S): Homo sapiens (Human) 
2024-01-26 | PXD045069 | Pride
Human Liver cell Lc-ms/ms 
ProteomicsSerum proteomics of wild type mice and Mdm2 adipocyte-specific knock-in mice fed high-fat diet
The serum samples from wild type mice fed high-fat diet for 12 weeks (WT_Serum) and Mdm2 adipocyte-specific knock-in mice fed high-fat diet for 12 weeks (KI_Serum) were mixed separately, and subjected to proteomic study by Label-free quantitative techniques and mass spectrometry-based proteomics tec...
ORGANISM(S): Mus musculus (Mouse) 
2022-08-11 | PXD034069 | Pride
Serum Proteomics Mice Wild type Mdm2 
ProteomicsThe eWAT proteomics of wild type mice and Mdm2 adipocyte-specific knock-in mice fed high-fat diet
The epididymal adipose tissue (eWAT) samples from wild type mice fed high-fat diet for 12 weeks (H_WT_E) and Mdm2 adipocyte-specific knock-in mice fed high-fat diet for 12 weeks (H_KI_E) were mixed separately, and subjected to proteomic study by Label-free quantitative techniques and mass spectromet...
ORGANISM(S): Mus musculus (Mouse) 
2022-08-11 | PXD034074 | Pride
Proteomics Ewat Mice Mdm2 High-fat diet 
UnknownComparative Proteomic Analysis of Lysine Acetylation in Fish CIK Cells Infected with Aquareovirus.
Not available
S-EPMC5713387 | biostudies-literature
TranscriptomicsTranslatome of A549, H1299 and HBE cells
We performed translatome and transcriptome sequencing of A549, H1299 and HBE cells and analyzed the translation ratio (TR) of all genes Total RNA and ribosome-bound RNA were extracted from A549, H1299 and HBE cells, and the polyA+ mRNA was sequenced using Illumina GAIIx and HiSeq-2000. The reads wer...
ORGANISM(S): Homo sapiens 
2013-03-05 | E-GEOD-42006 | biostudies-arrayexpress
UnknownGlobal analysis of HBV-mediated host proteome and ubiquitylome change in HepG2.2.15 human hepatoblastoma cell line.
Not available
S-EPMC8052555 | biostudies-literature
ProteomicsThe eWAT ubiquitinome of wild type mice and Mdm2 adipocyte-specific knock-in mice fed high-fat diet
The epididymal adipose tissue (eWAT) samples from wild type mice fed high-fat diet for 12 weeks (H_WT_E) and Mdm2 adipocyte-specific knock-in mice fed high-fat diet for 12 weeks (H_KI_E) were mixed separately, and subjected to ubiquitinome study by Label-free quantification and ubiquitination modifi...
ORGANISM(S): Mus Musculus 
2022-05-26 | PXD034127 |
ProteomicsXAB2 depletion induces intron retention in POLR2A to impair global transcription and promote cellular senescence
XAB2 is a multi-functional protein participating processes including transcription, splicing, DNA repair and mRNA export. Here we report POLR2A as a major target gene down-regulated after XAB2 depletion. XAB2 depletion led to severe splicing defects of POLR2A with significant intron retention. Such ...
ORGANISM(S): Homo sapiens (Human) 
2019-11-13 | PXD012552 | Pride
Xab2 Polr2a Hela cell 
ProteomicsGlobal profiling of Protein Lysine Lactylation in Mouse Cardiac Hypertrophy
In our study, we performed quantitative proteomics and Kla PTM analysis to investigate the alterations in protein lysine lactylation in a mouse model of cardiac hypertrophy. The results identified 159 Kla-modified sites across 80 proteins, with 72 proteins showing increased Kla levels in hypertrophi...
ORGANISM(S): Mus musculus (Mouse) 
2026-09-07 | PXD061494 | Pride
Lactylation Cardiac hypertrophy Mouse Heart failure 
ProteomicsMouse cortex immunoprecipitation-mass spectrometry
To determine the mechanism for how Kctd10 deficiency impacts brain development, co-immunoprecipitation (co-IP) was performed to identify KCTD10-interacting proteins from the E14.5 cerebral cortex using a KCTD10 antibody, followed by mass spectrometric analysis. In total, 143 proteins uniquely precip...
ORGANISM(S): Mus musculus (Mouse) 
2024-05-22 | PXD050135 | Pride
E14.5 Mouse Kctd10 Crebral cortex 
Sort   by:  
 Page size