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TranscriptomicsEvidence of Dynamically Dysregulated Gene Expression Pathways in Hyper-responsive B Cells from African American Lupus Patients
In this report we applied standard and original methods of analysis of gene expression microarray data to delineate differences in the molecular pathways impacted by stimulation of Epstein-Barr virus (EBV) transformed B cells derived from patients with systemic lupus erythematosus (SLE) and normal u...
ORGANISM(S): Homo sapiens 
2012-04-25 | E-GEOD-37573 | biostudies-arrayexpress
ProteomicsCharacterisation of CASQ2 knockout cardiac organoid model
Cardiac maturation is an important developmental phase where there are profound biological and functional changes after birth in mammals. Herein, we use our profiling of human heart maturation in vivo to identify key drivers of maturation in our human cardiac organoid (hCO) model. In this dataset, w...
ORGANISM(S): Homo sapiens (Human) 
2025-04-17 | PXD055266 | Pride
Calsequesterin Crispr Cardiac organoids 
ProteomicsModelling complex cardiovascular disease in mature organoid model
Cardiac maturation is an important developmental phase where there are profound biological and functional changes after birth in mammals. Herein, we use our profiling of human heart maturation in vivo to identify key drivers of maturation in our human cardiac organoid (hCO) model. In this dataset, w...
ORGANISM(S): Homo sapiens (Human) 
2025-04-17 | PXD054791 | Pride
Cardiac organoids Maturation Dsp Cardiomyopathy 
ProteomicsCharacterisation of directed maturation in human cardiac organoids
Cardiac maturation is an important developmental phase where there are profound biological and functional changes after birth in mammals. Herein, we use our profiling of human heart maturation in vivo to identify key drivers of maturation in our human cardiac organoid (hCO) model. After screening of...
ORGANISM(S): Homo sapiens (Human) 
2025-04-17 | PXD059940 | Pride
Maturation Cardiac organoids 
ProteomicsPhosphoproteomic response underpinning cardiac organoid maturation by electronic pacing and directed maturation media
Cardiac maturation is an important developmental phase where there are profound biological and functional changes after birth in mammals. Herein, we use our profiling of human heart maturation in vivo to identify key drivers of maturation in our human cardiac organoid (hCO) model. After screening of...
ORGANISM(S): Homo sapiens (Human) 
2025-04-17 | PXD054810 | Pride
Cardiac organoids Maturation Phosphorylation Pacing 
UnknownLatent autoimmunity across disease-specific boundaries in at-risk first-degree relatives of SLE and RA patients.
Not available
S-EPMC6491794 | biostudies-literature
UnknownTrans-Ethnic Mapping of BANK1 Identifies Two Independent SLE-Risk Linkage Groups Enriched for Co-Transcriptional Splicing Marks.
Not available
S-EPMC6121630 | biostudies-literature
UnknownMeta-analysis and imputation identifies a 109 kb risk haplotype spanning TNFAIP3 associated with lupus nephritis and hematologic manifestations.
Not available
S-EPMC2714405 | biostudies-literature
UnknownCombined role of vitamin D status and CYP24A1 in the transition to systemic lupus erythematosus.
Not available
S-EPMC5360632 | biostudies-literature
UnknownThe US Department of Veterans Affairs Science and Health Initiative to Combat Infectious and Emerging Life-Threatening Diseases (VA SHIELD): A Biorepository Addressing National Health Threats.
Not available
S-EPMC9801224 | biostudies-literature
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