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Acute myocardial infarction (AMI) is one of the leading causes of death. It is particularly important to predict malignant ventricular arrhythmia (MVA) timely and accurately in patients with AMI. This study aimed to explore biomarkers and to reveal possible mechanisms of MVA in AMI for clinical diag...
ORGANISM(S): Homo sapiens (Human) 
2024-01-26 | PXD041535 | Pride
Patent ductus arteriosus (PDA) is the third most common congenital heart disease and resulted from the persistence of ductal patency after birth. Ductus arteriosus closure involves functional and structural remodeling, controlled by many factors. The closure-related human plasma proteins are unknown...
ORGANISM(S): Homo sapiens (Human) 
2018-11-30 | PXD008568 | Pride
Recurrent miscarriage (RM) is the occurrence of repeated pregnancies that end in miscarriage of the fetus before 20 weeks of gestation. Recurrent miscarriages affect about 1-2% of couples trying to conceive; however, mechanisms leading to this complication are largely unknown. Our previous studies u...
ORGANISM(S): Homo sapiens (Human) 
2021-07-30 | PXD023849 | Pride
The role of modification of histone lysine 2-hydroxyisobutyrylation in atrial fibrillation is unclear and we hence explored the role of 2-hydroxyisobutyrylation in atrial fibrillation. Tandem Mass Tag proteomics method and other verification technologies in tissues and cells identified the protein p...
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD032154 | Pride
Lysine propionylation modification (Kpr) plays an important role in the pathogenesis of several cardiovascular diseases, but the role of Kpr in postoperative atrial fibrillation (POAF) is unclear. Here, we established an atlas of proteomics and propionylation proteomics in the atrial appendage tissu...
ORGANISM(S): Homo sapiens (Human) 
2025-08-11 | PXD059607 | Pride
We performed 4D-labelfree quantitative proteomics analysis of right atrial appendage tissues from 5 patients with atrial fibrillation (AF) and 5 patients with sinus rhythm (SR) after CABG. A total of 2179,559 spectrums and 48,047 peptides were detected by mass spectrometry. Further, we identified 50...
ORGANISM(S): Homo sapiens (Human) 
2025-08-11 | PXD059685 | Pride
Purpose: Damage to the uterosacral ligaments is an important contributor to uterine and vaginal prolapse. The aim of this study was to identify differentially expressed proteins in the uterosacral ligaments of women with and without pelvic organ prolapse and analyze their relationships to cellular...
ORGANISM(S): Homo sapiens (Human) 
2018-12-10 | PXD011467 | Pride
Postoperative atrial fibrillation (POAF) is a common complication in coronary artery bypass grafting (CABG). We investigated pre-existing biological derangements before CABG to provide molecular insights into the pathogenesis. Preoperative plasma samples of discovery set from matched cohorts in sinu...
ORGANISM(S): Homo Sapiens 
2018-10-17 | PXD011383 |

Leprosy is a chronic infectious disease caused by Mycobacterium leprae (M. leprae). Due to M. leprae's narrow host range and an inability to be cultured in vitro, the biological investigation of this disease has been difficult. Host genetic factors have been ...

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