Sort   by:  
 Page size 
ProteomicsProteomics reveals dynamic assembly of repair complexes during bypass of DNA cross-links part 2 of 2: AP-MS DATA (QUBIC)
DNA interstrand crosslinks (ICLs) block replication fork progression by inhibiting DNA strand separation. Repair of ICLs requires sequential incisions, translesion DNA synthesis, and homologous recombination, but the full set of factors involved in these transactions remains unknown. Here we establi...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-03-13 | MSV000079577 | MassIVE
ProteomicsespL deletion mutant of Mycobacterium tuberculosis
The ESX-1, type VII, secretion system represents the major virulence determinant of Mycobacterium tuberculosis, one of the most successful intracellular pathogens. Here, by combining genetic and high-throughput approaches, we show that EspL, a protein of 115 amino acids, is essential for mediating E...
ORGANISM(S): Mycobacterium tuberculosis H37Rv 
2018-12-10 | PXD010929 | Pride
Mycobacterium Virulence Tuberculosis Espl 
ProteomicsSelective Macrocyclic Peptide Modulators of Lys63-linked Ubiquitin Chains Disrupt DNA Damage Repair
Developing an effective binder for a specific ubiquitin (Ub) chain is a promising approach for modulating various biological processes with potential applications in drug discovery. In this study, we combined the Random Non-standard Peptides Integrated Discovery (RaPID) method and chemical protein s...
ORGANISM(S): Homo sapiens (Human) 
2022-09-19 | PXD035924 | Pride
Ubiquitin Dna damage repair 
OtherA proteomic ruler for protein copy number and concentration estimation without spike-in standards.
Data from ProteomeXchange, PXD ID: PXD000661. Experiment: A549, file: 20121023_EXQ4_JRW_SA_32L_3.mzml. Published as part of Mol Cell Proteomics. 2014 Sep 15 . From the Abstract: {{i}} ... Here we present a novel concept that delivers similar quantitative results directly from deep eukaryotic proteo...
ORGANISM(S): Homo_sapiens_viruses, Human 
GPM32320003525 | GPMDB
Resource Reanalysis 
OtherA proteomic ruler for protein copy number and concentration estimation without spike-in standards.
Data from ProteomeXchange, PXD ID: PXD000661. Experiment: TPA_Lung, file: 20120207_EXQ6_JRW_TPA_Lung_28_1_T.mzml. Published as part of Mol Cell Proteomics. 2014 Sep 15 . From the Abstract: {{i}} ... Here we present a novel concept that delivers similar quantitative results directly from deep eukary...
ORGANISM(S): Mus_musculus_viruses, Mouse 
GPM11210029853 | GPMDB
Resource Reanalysis 
GenomicsMelanoma - Exome sequencing
Direct identification of clinically relevant neoepitopes presented on native human melanoma tissue by mass spectrometry - Exome sequencing
PRJEB15496 | ENA
ProteomicsA Mitochondria-Driven Quality Control Pathway Eliminates Mislocalized Peroxisomal Membrane Proteins
Protein quality control (PQC) systems are essential for maintaining a healthy proteome by removing aberrant proteins, including mislocalized proteins. However, the mechanisms for eliminating mislocalized Peroxisomal Membrane Proteins (PMPs) have remained elusive. Here, using quantitative proteomics ...
ORGANISM(S): Homo sapiens (Human) 
2026-05-14 | PXD069489 | Pride
Peroxisome Protein degradation March5 E3 ligases Mul1 Ubiquitin Protein quality control Peroxisomal membrane proteins (pmps) 
TranscriptomicsDecoding human cytomegalovirus using ribosome profiling
The human cytomegalovirus (HCMV) genome was sequenced 20 years ago. However, like other complex viruses, our understanding of its protein coding potential is far from complete. Here, we use ribosome profiling and transcript analysis to experimentally define the HCMV translation products and follow t...
ORGANISM(S): Human Herpesvirus 5 
2012-10-17 | E-GEOD-41605 | biostudies-arrayexpress
ProteomicsA human interactome in three quantitative dimensions organized by stoichiometries and abundances -- auxiliary dataset
The organization of a cell emerges from the interactions in protein networks. The interactome is critically dependent on the strengths of interactions and the cellular abundances of the connected proteins, both of which span orders of magnitude. However, these aspects have not yet been analyzed glob...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Saccharomyces Cerevisiae (ncbitaxon:4932) Mus Musculus (ncbitaxon:10090) 
2016-10-21 | MSV000080271 | MassIVE
ProteomicsA human interactome in three quantitative dimensions organized by stoichiometries and abundances
The organization of a cell emerges from the interactions in protein networks. The interactome is critically dependent on the strengths of interactions and the cellular abundances of the connected proteins, both of which span orders of magnitude. However, these aspects have not yet been analyzed glob...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Mus Musculus (ncbitaxon:10090) 
2016-06-17 | MSV000079835 | MassIVE
Sort   by:  
 Page size