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ProteomicsKinome Profiling of Primary Endometrial Tumors Using Multiplexed Inhibitor Beads and Mass Spectrometry Identifies SRPK1 As A Candidate Therapeutic Target
Protein kinases (collectively termed the kinome) represent one of the most tractable drug targets in the pursuit of new and effective cancer treatments. However, less than 20% of the kinome is currently being explored as primary targets for cancer therapy, leaving the majority of the kinome untarget...
ORGANISM(S): Homo sapiens (Human) 
2020-09-30 | PXD020357 | Pride
Endometrial Srpk1 
ProteomicsIdentification of MRCKA as an integral component of ovarian cancer signaling and a therapeutic target
High-grade serous ovarian carcinoma (HGSOC) is the most lethal gynecological cancer with few effective targeted therapies. HGSOC tumors exhibit genomic instability with frequent alterations in the protein kinome; however, only a small fraction of the kinome has been therapeutically targeted in HGSOC...
ORGANISM(S): Homo sapiens (Human) 
2020-02-19 | PXD015849 | Pride
Human Mrcka High grade serous ovarian carcinoma Cdc42bpa 
UnknownHigh-Quality Draft Genome Sequence of Bacillus amyloliquefaciens Strain 629, an Endophyte from Theobroma cacao.
Not available
S-EPMC4653783 | biostudies-literature
UnknownWhole Genome Sequencing and Characteristics of mcr-1-Harboring Plasmids of Porcine Escherichia coli Isolates Belonging to the High-Risk Clone O25b:H4-ST131 Clade B.
Not available
S-EPMC7105644 | biostudies-literature
TranscriptomicsHuman liver stem cells-derived microvesicles accelerate hepatic regeneration in partially hepatectomized rats
Several studies indicate that adult stem cells may improve the recovery from acute tissue injury. It has been suggested that they may contribute to tissue regeneration by the release of paracrine factors promoting proliferation of tissue resident cells. However, the factors involved remain unknown. ...
ORGANISM(S): Homo sapiens 
2010-05-08 | E-GEOD-15569 | biostudies-arrayexpress
UnknownA chromosome-scale genome assembly of the false clownfish, Amphiprion ocellaris.
Not available
S-EPMC9073690 | biostudies-literature
UnknownFirst detection of SARS-CoV-2 variant B.1.1.529 (Omicron) in Ecuador.
Not available
S-EPMC8739794 | biostudies-literature
UnknownEmerging Cancer Immunotherapies: Cutting-Edge Advances and Innovations in Development.
Not available
S-EPMC11417735 | biostudies-literature
TranscriptomicsGenetic characterization of tumor-stage mycosis fungoides
Mycosis fungoides patients who develop tumors or extracutaneous involvement usually have a poor prognosis with no curative therapy available so far. In the present EORTC multicenter study, the genomic profile of 41 skin biopsies from tumor-stage mycosis fungoides was analyzed using a high-resolution...
ORGANISM(S): Homo sapiens 
2010-05-06 | E-GEOD-18098 | biostudies-arrayexpress
UnknownVagal blocking improves glycemic control and elevated blood pressure in obese subjects with type 2 diabetes mellitus.
Not available
S-EPMC3745954 | biostudies-literature
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