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ProteomicsDiscovery of a small molecule inhibitor of the UBE2F-CRL5 axis that induces apoptosis and G2/M arrest and confers radiosensitization
Protein neddylation modification is catalyzed by a neddylation activating enzyme (NAE, E1), an E2 conjugating enzyme and an E3 ligase. In various types of human cancers, the neddylation pathway was abnormally activated. Our previous study validated that neddylation E2 UBE2F is a promising lung cance...
ORGANISM(S): Homo sapiens (Human) 
2022-10-19 | PXD036191 | Pride
Ube2f  neddylation  apoptosis  cell cycle arrest  small molecule inhibitor 
UnknownUnique structural solution from a VH3-30 antibody targeting the hemagglutinin stem of influenza A viruses.
Not available
S-EPMC7835374 | biostudies-literature
ProteomicsPattern Analysis of Organellar Maps for Interpretation of Pro-teomic Data
The human proton-coupled folate transporter (PCFT) was stably expressed as a fu-sion protein with a BioID2-HA in the C-terminal position (PCFT-BioID2). The uncom-plxed biotin transferase was used as a control to identify proteins that are biotinylated randomly due to sheer abundance and/or an unnatu...
ORGANISM(S): Homo sapiens (Human) 
2022-06-09 | PXD032297 | Pride
Proteomics  pattern analysis  bioinformatics  proximity labeling 
TranscriptomicsSmall RNA Solexa sequencing of human liver samples
We applied small RNA Solexa sequencing technology to identify microRNA expression in human liver samples from surgically removed liver tissues including three normal liver tissues (distal normal liver tissue of liver hemangioma), an hepatitis B virus (HBV)-infected liver, a severe chronic hepatitis ...
ORGANISM(S): Homo sapiens 
2010-04-10 | E-GEOD-21279 | biostudies-arrayexpress
ProteomicsIdentification of lysine sites in RIG-I ubiquitinated by RNF167 through mass spectrometry analysis
To identify RNF167-catalyzed ubiquitinated peptides of RIG-I
ORGANISM(S): Homo sapiens (Human) 
2025-02-07 | PXD060570 | Pride
Lc-ms Ubiquitination 
ProteomicsPhosphorylation site identifcaiton of OsHSFA4d
To identify the residues of OsHSFA4d phosphorylated by OsCDPK24, the in vitro kinase assays were conducted by incubating recombinant MBP-HA-OsCDPK24 + GST-OsHSFA4d and MBP-HA + GST-OsHSFA4d. The reaction was terminated by adding SDS loading buffer to a 1×concentration, and the reaction products were...
ORGANISM(S): Oryza sativa (Rice) 
2025-06-09 | PXD064745 | Pride
Phosphorylation site  oshsfa4d 
UnknownThe Relationship between Osteoinduction and Vascularization: Comparing the Ectopic Bone Formation of Five Different Calcium Phosphate Biomaterials.
Not available
S-EPMC9146137 | biostudies-literature
UnknownTheoretical and Experimental Investigation of the Antioxidation Mechanism of Loureirin C by Radical Scavenging for Treatment of Stroke.
Not available
S-EPMC9822359 | biostudies-literature
UnknownExogenous salicylic acid treatment enhances the disease resistance of Panax vietnamensis by regulating secondary metabolite production.
Not available
S-EPMC11362055 | biostudies-literature
TranscriptomicsThe differentially expressed genes in rice jmj704 mutants revealed through RNA-Seq
We sequenced mRNA from two-week old rice seedlings of jmj704 and wild-type (ZH11) plants to obtain the differntially expressed genes in jmj704 mutant. exzamination the differentially expressed genes between two-week old jmj704 and wild-type (ZH11) rice seedlings.
ORGANISM(S): Oryza sativa 
2015-11-05 | E-GEOD-74670 | biostudies-arrayexpress
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