Sort   by:  
 Page size 
ProteomicsProteomics Study and Protein Biomarkers of Malignant Ventricular Arrhythmia in Acute Myocardial Infarction Patients
Acute myocardial infarction (AMI) is one of the leading causes of death. It is particularly important to predict malignant ventricular arrhythmia (MVA) timely and accurately in patients with AMI. This study aimed to explore biomarkers and to reveal possible mechanisms of MVA in AMI for clinical diag...
ORGANISM(S): Homo sapiens (Human) 
2024-01-26 | PXD041535 | Pride
Acute myocardial infarction  malignant ventricular arrhythmia  proteomics  data independent acquisition 
ProteomicsHuman plasma LC-MSMS - Altered plasma proteins released from platelets and endothelial cells are associated with human patent ductus arteriosus
Patent ductus arteriosus (PDA) is the third most common congenital heart disease and resulted from the persistence of ductal patency after birth. Ductus arteriosus closure involves functional and structural remodeling, controlled by many factors. The closure-related human plasma proteins are unknown...
ORGANISM(S): Homo sapiens (Human) 
2018-11-30 | PXD008568 | Pride
Human Patent ductus arteriosus Plasma Proteomics Lc-msms 
ProteomicsHuman atrial tissue modification of Lysine 2-hydroxyisobutyrylation
The role of modification of histone lysine 2-hydroxyisobutyrylation in atrial fibrillation is unclear and we hence explored the role of 2-hydroxyisobutyrylation in atrial fibrillation. Tandem Mass Tag proteomics method and other verification technologies in tissues and cells identified the protein p...
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD032154 | Pride
Post-translational modification Human 2-hydroxyisobutyrylation 
ProteomicsAtlas of lysine propionylation in the human right atrium reveals ALDH6A1-NADH pathway involved in the new-onset atrial fibrillation in aging after coronary artery bypass grafting
Lysine propionylation modification (Kpr) plays an important role in the pathogenesis of several cardiovascular diseases, but the role of Kpr in postoperative atrial fibrillation (POAF) is unclear. Here, we established an atlas of proteomics and propionylation proteomics in the atrial appendage tissu...
ORGANISM(S): Homo sapiens (Human) 
2025-08-11 | PXD059607 | Pride
Propionylation Aldh6a1 Atrial fibrillation Coronary artery bypass grafting 
ProteomicsProteomics study of right atrium in patients with atrial fibrillation after coronary artery bypass grafting
We performed 4D-labelfree quantitative proteomics analysis of right atrial appendage tissues from 5 patients with atrial fibrillation (AF) and 5 patients with sinus rhythm (SR) after CABG. A total of 2179,559 spectrums and 48,047 peptides were detected by mass spectrometry. Further, we identified 50...
ORGANISM(S): Homo sapiens (Human) 
2025-08-11 | PXD059685 | Pride
Proteomics Right atrial appendage Atrial fibrillation 
ProteomicsPropionylation at OXCT1 lysine-296 is the key mechanism of atrial fibrillation in both patients and atrial-specific knockout of the LKB1 mouse model
Atrial fibrillation (AF), the most prevalent clinical arrhythmia, imposes a major global health burden through elevated risks of stroke, heart failure, and mortality. Lysine propionylation (Kpr) is mainly involved in metabolic regulation and plays an important role in cardiac pathophysiology. Howeve...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2026-08-07 | PXD067998 | Pride
Atrial fibrillation Lkb1 Oxct1 Oxidative stress Protein post-translational modifications Propionylation 
ProteomicsAnalysis of the preoperative plasma samples of sinus rhythm and POAF in CABG using Proteomic study
Postoperative atrial fibrillation (POAF) is a common complication in coronary artery bypass grafting (CABG). We investigated pre-existing biological derangements before CABG to provide molecular insights into the pathogenesis. Preoperative plasma samples of discovery set from matched cohorts in sinu...
ORGANISM(S): Homo Sapiens 
PXD011383 |
GenomicsGenome wide association study of leprosy in Chinese population

Leprosy is a chronic infectious disease caused by Mycobacterium leprae (M. leprae). Due to M. leprae's narrow host range and an inability to be cultured in vitro, the biological investigation of this disease has been difficult. Host genetic factors have been ...

phs000217.v1.p1 | EGA
UnknownFine mapping of genetic variants in BIN1, CLU, CR1 and PICALM for association with cerebrospinal fluid biomarkers for Alzheimer's disease.
Not available
S-EPMC3036586 | biostudies-literature
Sort   by:  
 Page size