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ProteomicsLabel-Free Phosphoproteomics Profiling of Fission Yeast Schizosaccharomyces pombe
The phosphorylation of proteins modulates various functions of proteins and plays an important role in regulation of cell signaling. In the recent years, the label-free quantitative (LFQ) phos-phoproteomics has become the powerful tool to analyze the phosphorylation of proteins within the complex sa...
ORGANISM(S): Schizosaccharomyces pombe 927 
2021-02-12 | PXD023818 | Pride
Pgc Schizosaccharomyces pombe Sax Lfq phosphoproteomics 
ProteomicsHipSci project pilot submission for 18 IPS cell lines
The Human Induced Pluripotent Stem Cells Initiative (HipSci) is generating a large, high-quality reference panel of human IPSC lines. This is a pilot submission of mass-spectrometry analyses from 18 induced pluripotent stem cell lines generated by the HipSci project. This submission includes also da...
ORGANISM(S): Homo sapiens (Human) 
2016-06-06 | PXD003903 | Pride
Human Label free quantitative proteomics Hplc fractionation (sax) Pluripotent Ips cells 
UnknownStatistical learning of peptide retention behavior in chromatographic separations: a new kernel-based approach for computational proteomics.
Not available
S-EPMC2254445 | biostudies-literature
ProteomicsDIA-MS analysis of 21 breast cancer tissues
In recent years genomic and proteomic technologies have been employed in a combined effort to extrapolate key clinical and biological information of complex diseases such as cancer. Most integrative studies employ DNA and/or RNA sequencing technologies coupled to mass spectrometry-derived informatio...
ORGANISM(S): Homo sapiens (Human) 
2021-04-26 | PXD018830 | Pride
Data independent acquisition Human Breast cancer Proteome 
ProteomicsDeep spatial proteomics reveals region-specific features of severe COVID-19-related pulmonary injury
As a primary target of SARS-CoV-2, lung exhibits heterogeneous histopathological changes following infection. However, comprehensive insight into their protein basis with spatial resolution remains deficient, which hinders further understanding of COVID-19-related pulmonary injury. Here, we generate...
ORGANISM(S): Homo sapiens (Human) 
2024-01-22 | PXD043807 | Pride
Covid-19 Laser microdissection Pathology Lung Autopsy Spatial proteomics 
ProteomicsProteomic profiling of cathepsin specificity by FPPS
Identification of protease substrates and determination of their specificities can provide important insights into their function. In the past decade, several proteomic approaches for identification of protease cleavage sites were developed, each relying on various strategies for peptide labelling a...
ORGANISM(S): Homo sapiens (Human) 
2015-02-10 | PXD001553 | Pride
Degradomics Proteases Cathepsins 
ProteomicsDIA-MS analysis of 24 breast cancer tissues
In recent years genomic and proteomic technologies have been employed in a combined effort to extrapolate key clinical and biological information of complex diseases such as cancer. Most integrative studies employ DNA and/or RNA sequencing technologies coupled to mass spectrometry-derived informatio...
ORGANISM(S): Homo sapiens (Human) 
2021-04-26 | PXD021394 | Pride
Human Breast cancer Dia 
ProteomicsFish coelomic fluid proteomic analysis by LC-MSMS
The aim of this study was to complete and fully characterize the proteome of rainbow trout coelomic fluid (CF). Furthermore, we intended to identify the proteins responsible for the extension of egg viability in salmonids coelomic fluid. For this, the proteomic composition of different salmonids CF ...
ORGANISM(S): Acipenser gueldenstaedtii Sander lucioperca Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri) Salmo salar (Atlantic salmon) Salmo trutta Cyprinus carpio (Common carp) Acipenser baerii Carassius auratus 
2024-05-21 | PXD034989 | Pride
Lc-msms Fish Coelimic fluid 
ProteomicsProteomic characterization of ESR1 mutant cells
Three quarters of all breast cancer cases express the estrogen receptor (ER, ESR1 gene), which promotes tumor growth and constitutes a direct target for endocrine therapies. ESR1 mutations have been implicated in therapy resistance in metastatic breast cancers, in particular to aromatase inhibitors....
ORGANISM(S): Homo sapiens (Human) 
2024-03-26 | PXD032369 | Pride
Esr1 mutation Breast cancer 
ProteomicsPhosphoproteome characterization of ESR1 mutated breast cancer cells
Three quarters of all breast cancer cases express the estrogen receptor (ER, ESR1 gene), which promotes tumor growth and constitutes a direct target for endocrine therapies. ESR1 mutations have been implicated in therapy resistance in metastatic breast cancers, in particular to aromatase inhibitors....
ORGANISM(S): Homo sapiens (Human) 
2024-03-26 | PXD032285 | Pride
Phosphoproteome Esr1 mutations Breast cancer 
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