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ProteomicsHuman lymphoma cell membrane proteomics by Pitchfork strategy
We combined glycopeptide enrichment by SPEG (Tian et al., 2007) with a hydrophobic segment-oriented hpTC method (Vít et al 2016) and a standard “detergent and trypsin” approach into a tree-pronged “Pitchfork” strategy for the analysis of membrane proteome in human lymphoma cells.
ORGANISM(S): Homo sapiens (Human) 
2019-03-29 | PXD012647 | Pride
Lymphoma Membrane proteins Imp Hptc Speg 
GenomicsIdentify and characterize the polyploidization process of primary human proximal tubular cells (hPTC)
Identify and characterize the polyploidization process of primary human proximal tubular cells (hPTC)
PRJNA874743 | ENA
GenomicsIdentify and characterize the polyploidization process of primary human proximal tubular cells (hPTC) [scRNA-seq]
Identify and characterize the polyploidization process of primary human proximal tubular cells (hPTC) [scRNA-seq]
PRJNA1014368 | ENA
TranscriptomicsIdentify and characterize the polyploidization process of primary human proximal tubular cells (hPTC)
We generated single-cell RNA sequencing (scRNAseq) datasets of primary cultures of human proximal tubular cells at different passages which we have found to contain a polyploid fraction. Within hPTC clusters, we found genes previously associated with different phases of endoreplication-mediated poly...
ORGANISM(S): Homo sapiens 
2022-10-01 | GSE212275 | GEO
ProteomicsDeep membrane proteome profiling of high-risk human paraganglioma
We combined glycopeptide enrichment by N-glyco-FASP (Zielinska et al., 2010), SPEG (Tian et al., 2007) with a hydrophobic segment-oriented hpTC method (Vít et al 2016) and a standard “detergent and trypsin” approach into a tree-pronged “Pitchfork” strategy for the analysis of membrane proteome in hi...
ORGANISM(S): Homo sapiens (Human) 
2021-11-25 | PXD029344 | Pride
Lc-msms Paraganglioma Membrane proteome Human Pitchfork strategy 
TranscriptomicsIdentify and characterize the polyploidization process of primary human proximal tubular cells (hPTC) [scRNA-seq]
We generated single-cell RNA sequencing (scRNAseq) datasets of primary cultures of human proximal tubular cells stimulated with TGF-β1 or vehicle. Following TGF-β1 stimulation, hPTC expressed TGF-β1 and its downstream targets. Moreover, TGF-β1-treated hPTC were characterized by a differential expres...
ORGANISM(S): Homo sapiens 
2023-09-08 | GSE242695 | GEO
TranscriptomicsNew insight into a host-pathogen interaction unveiled by transcriptomics response of the global insect pest Plutella xylostella to a fungal pathogen
A genomic insight into how an insect pest responds to the infection of a fungal insect pathogen, such as Beauveria bassiana, is critical for alternative strategy of insect pest contol based on fungal insecticides but has not been well probed. Here we constructed three pairs of digital expression lib...
ORGANISM(S): Plutella xylostella 
2016-04-06 | E-GEOD-72383 | biostudies-arrayexpress
ProteomicsComprehensive proteomic characterization identifies potential molecular targets for therapy and imaging in the Cluster 1 human pheochromocytoma and paraganglioma
In order to identify new proteins with a potential to become targets for therapy or tumor imaging in pheochromocytoma and paraganglioma, we performed detailed proteomic analysis of 22 well-characterized human PPGL samples and normal chromaffin tissue from adrenal medulla. A standard quantitative pro...
ORGANISM(S): Homo sapiens (Human) 
2023-09-25 | PXD039788 | Pride
Surface proteins Pheochromocytoma Paraganglioma Pitchfork strategy Membrane proteome Human 
UnknownNLRP3 Localizes to the Tubular Epithelium in Human Kidney and Correlates With Outcome in IgA Nephropathy.
Not available
S-EPMC4837396 | biostudies-literature
UnknownEmpagliflozin Inhibits Basal and IL-1β-Mediated MCP-1/CCL2 and Endothelin-1 Expression in Human Proximal Tubular Cells.
Not available
S-EPMC7663377 | biostudies-literature
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