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TranscriptomicsspeG affects intracellular replication, polyamine metabolism, and transcriptomes of Salmonella
The speG gene has been reported to regulate polyamine metabolism in Escherichia coli and Shigella, but its role in Salmonella remains unknown. Our preliminary studies have revealed that speG widely affects the transcriptomes of infected in vitro M and Caco-2 cells and that it is required for the int...
ORGANISM(S): Salmonella enterica subsp. enterica serovar Typhimurium str. SL1344 
2017-08-22 | GSE102885 | GEO
ProteomicsIntegrated multi-omics approach reveals the role of SPEG in skeletal muscle biology including its relationship with myospryn complex
We applied multi-omics approaches (interactomic, proteomic, phosphoproteomic, and transcriptomic analyses) to assess underlying molecular pathways impacted by SPEG using mouse skeletal muscle from 2-month-old WT (n=4) and Speg-CKO (n=3) mice.
ORGANISM(S): Mus musculus (Mouse) 
2024-06-22 | PXD041692 | Pride
Lc-msms Mouse skeletal muscle 
ProteomicsHuman lymphoma cell membrane proteomics by Pitchfork strategy
We combined glycopeptide enrichment by SPEG (Tian et al., 2007) with a hydrophobic segment-oriented hpTC method (Vít et al 2016) and a standard “detergent and trypsin” approach into a tree-pronged “Pitchfork” strategy for the analysis of membrane proteome in human lymphoma cells.
ORGANISM(S): Homo sapiens (Human) 
2019-03-29 | PXD012647 | Pride
Lymphoma Membrane proteins Imp Hptc Speg 
UnknownExploring Obscurin and SPEG Kinase Biology.
Not available
S-EPMC7957886 | biostudies-literature
UnknownNovel SPEG mutations in congenital myopathies: Genotype-phenotype correlations.
Not available
S-EPMC7288247 | biostudies-literature
UnknownCharacterization of a novel zebrafish model of SPEG-related centronuclear myopathy.
Not available
S-EPMC9118044 | biostudies-literature
UnknownSPEG-deficient skeletal muscles exhibit abnormal triad and defective calcium handling.
Not available
S-EPMC5905626 | biostudies-literature
UnknownThe spermidine acetyltransferase SpeG regulates transcription of the small RNA rprA.
Not available
S-EPMC6298664 | biostudies-literature
UnknownSPEG interacts with myotubularin, and its deficiency causes centronuclear myopathy with dilated cardiomyopathy.
Not available
S-EPMC4129406 | biostudies-literature
UnknownNovel SPEG variant cause centronuclear myopathy in China.
Not available
S-EPMC7031609 | biostudies-literature
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