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This study aims to identify the proteins co-precipitated with anti-Hsc70 antibody
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2025-04-11 | PXD058521 | Pride
we compared the interacting proteins between Hsc70-WT and Hsc70-3KA using mass spectrometry to discover additional mediators of this process
ORGANISM(S): Homo Sapiens 
HSC70 is the cytosolic isoform of plant HSP70. We have found that HSC70 family proteins bind to the heat shock transcription factor A1s (HsfA1s), which are the master regulators of the heat shock response in plants, and supress their activity. To investigate the role of HSC70s in the regulation of H...
ORGANISM(S): Arabidopsis thaliana 
HSC70 is the cytosolic isoform of plant HSP70. We have found that HSC70 family proteins bind to the heat shock transcription factor A1s (HsfA1s), which are the master regulators of the heat shock response in plants, and suppress their activity. We additionally found that the triple knock out of HSC7...
ORGANISM(S): Arabidopsis thaliana 
quantitative identification of Hsc70 clients using co-IP fallowed by nano-LC-MS/MS in autophagy altered K-ras mutant MEF cells.
ORGANISM(S): Mus Musculus (mouse) 
LACTB inhibits lipid synthesis to suppress glioma growth by promoting Hsc70-mediated ERBB3 degradation
The heat shock response is a universal transcriptional response to proteotoxic stress orchestrated by heat shock transcription factor Hsf1 in all eukaryotic cells. Despite over 40 years of intense research, the mechanism of HSF1 activity regulation remains poorly understood at a molecular level. In ...
ORGANISM(S): Homo sapiens (Human) 
2020-06-22 | PXD017406 | Pride
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