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ProteomicsIdentification ubiquitination of EGFR by LC-MS/MS
Previously, analysis of EGF-induced EGFR ubiquitination by mass spectrometry revealed that ubiquitinated lysine residues were located in the TKD of EGFR. However, the specific lysine residues for the CBL-mediated polyubiquitination have not been identified. To investigate the differences in EGFR ubi...
ORGANISM(S): Homo sapiens (Human) 
2021-09-10 | PXD024279 | Pride
Cbl Ubiquitination Znrf1 Egfr Lc-ms/ms 
ProteomicsIdentification of the intermolecular disulfide bonds between NPGPx and ZAP70
The tyrosine kinase, ζ-chain-associated protein of 70 kDa (ZAP70), is essential for T cell development and activation. However, it remains elusive whether a direct redox regulation affects ZAP70 activity upon TCR stimulation. Here, we showed that deficiency of non-selenocysteine containing phospholi...
ORGANISM(S): Homo sapiens (Human) 
2021-01-25 | PXD017034 | Pride
Zap70 Npgpx Disulfide bond 
ProteomicsIdentification of NPGPx-interacting proteins in activated T cells
The tyrosine kinase, ζ-chain-associated protein of 70 kDa (ZAP70), is essential for T cell development and activation. However, it remains elusive whether a direct redox regulation affects ZAP70 activity upon TCR stimulation. Here, we showed that deficiency of non-selenocysteine containing phospholi...
ORGANISM(S): Homo sapiens (Human) 
2021-01-25 | PXD017046 | Pride
T cell activation Zap70 Npgpx 
ProteomicsMature B cell homeostasis, B cell activation and antibody response require protein O-GlcNAcylation
Proteins identified in sWGA versus anti-IgM pull-down assay.
ORGANISM(S): Mus musculus (Mouse) 
2017-11-13 | PXD007050 | Pride
O-glcnacylation/ b cells/ homeostasis/activation 
ProteomicsMouse brain LC-MS data in DWI-T2 mismatch area after cerebral ischemia
In ischemic stroke, DWI-T2 mismatch (positive signals on DWI but negative signals on T2) indicates ischemia within 4.5 h. However, the molecular expression pattern of this region remains elusive. This project aimed to reveal the proteomics profiling of the brain tissues at DWI-T2 mismatch, T2(+), an...
ORGANISM(S): Rattus norvegicus (Rat) 
2022-02-17 | PXD027890 | Pride
Ischemic stroke Brain Mouse Lc-ms Dwi-t2 mismatch area 
UnknownOral bioavailable ITRI-148 degrades androgen receptor variants and overcomes antiandrogen resistance in advanced prostate cancer.
Not available
S-EPMC12661400 | biostudies-literature
UnknownRobust estimation of bacterial cell count from optical density.
Not available
S-EPMC7499192 | biostudies-literature
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