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Neuron development requires an elaborate network of endosomal transport pathways, defects in which underlie multiple neurological diseases. DENND10/FAM45A is an ancient protein that is important for endosomal homeostasis. However, the role of DENND10 in the nervous system remained unknown. Here, we ...
ORGANISM(S): Mus musculus (Mouse) 
2025-03-06 | PXD038623 | Pride
We generated a P4ha2 knock-out mouse line (C57BL/6) by using CRISPR-Cas9 system. By mass spectrum, reduced proline hydroxylation was observed in collagens isolated from skin, sclera and cornea of P4ha2-/- mice.
ORGANISM(S): Mus musculus (Mouse) 
2026-03-02 | PXD023006 | Pride
Proteomics dataset of COVID-19 and control patients
ORGANISM(S): Homo Sapiens 
2021-10-14 | PXD029023 |
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