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GenomicsDynamically reorganized chromatin is the key for the reprogramming of somatic cells to pluripotent cells
We investigated genome-wide nucleosome coverage and histone methylation occupancies in somatic MEFs, intermediate pre-iPSCs and fully reprogrammed iPSCs. We found that nucleosome occupancies increased in promoter regions and decreased in intergenic regions in pre-iPSCs and then recover to an interme...
ORGANISM(S): Mus musculus 
2015-12-13 | E-GEOD-60627 | biostudies-arrayexpress
ProteomicsDPF3 and SNIP1 IP-MS in 786-O cells
In this project, we performed DPF3 and SNIP1 immunoprecipitation followed by mass spectrometry analysis to identify their interacting partners.
ORGANISM(S): Homo sapiens (Human) 
2022-08-22 | PXD033421 | Pride
Dpf3 Snip1 
ProteomicsIdentification of E2f1 interactors during early embryonic development in Xenopus tropicalis
In this project, we performed E2f1 immunoprecipitation followed by mass spectrometry analysis to identify its interacting partners during early embryonic development in Xenopus tropicalis.
ORGANISM(S): Xenopus tropicalis 
2025-12-01 | PXD051084 | Pride
Early embryonic development E2f1 Xenopus tropicalis 
ProteomicsEffective Enrichment Strategy Using Boronic Acid Functionalized Mesoporous Graphene Silica Composites for Intact Glycopeptide Analysis in Human Serum
The heterogeneity and low abundance of protein glycosylation present challenging barriers to the analysis of intact glycopeptides, which is key to comprehensively understanding the role of glycosylation in an organism. Efficient and specific enrichment of intact glycopeptides could help greatly with...
ORGANISM(S): Human 
2021-04-28 | MSV000087324 | MassIVE
ProteomicsThe inhibition effect of ERAP1-IN-1 on HepG2.2.15 cells
In our strudy, we preterated HepG2.2.15 cells with specific ERAP1 inhibitor ERAP1-IN-1(50μM). And then LC-MS/MS analysis was performed on a timsTOF Pro mass spectrometer.Finally we found that among the total peptides identified, ERAP1-IN-1-treated group had an reduction of the numbers of long pepti...
ORGANISM(S): Homo Sapiens 
2022-02-24 | PXD031858 |
ProteomicsLongitudinal proteomic investigation of COVID-19 vaccination
163 participants with paired peripheral blood mononuclear cells and serum samples，at D0, D28, day 57 (D57) by TMT-based proteomics
ORGANISM(S): Homo Sapiens 
2023-09-06 | PXD039826 |
ProteomicsTemporal proteomics characterization of COVID-19 patient sera
We enrolled 37 SARS-CoV-2 positive patients including 17 short course (SC) COVID-19 patients (twice viral RNA detection negative over 24 hrs) and 20 COVID-19 long course (LC) COVID-19 patients. We also included 35 SARS-CoV-2 negative patients as control group. We collected 224 inactive serum samples...
ORGANISM(S): Homo Sapiens 
PXD035471 |
ProteomicsCirculating Exosomes proteome of Colorectal Cancer Based on Rapid DIA-MS
Early screening is essential for the treatment of colorectal cancer (CRC). Concerns are rising regarding liquid biopsy due to its low invasiveness and reproducibility, especially when tissue samples are not available. Recent reports suggest that tumor-specific proteins may be stably expressed in exo...
ORGANISM(S): Homo Sapiens 
PXD015921 |
ProteomicsRaw data of 218 FFPE tissue proteomes containing 144 tissue samples from seven organs of fatal VID-19 cases and 74 control specimens from 56 non-COVID-19 individuals
144 tissue samples from postmortem lung, liver, kidney, heart, spleen, testis and thyroid collected from 19 COVID-19 cases and 74 control specimens from 56 non-COVID-19 individuals were analyzed by PCT and TMT 16-plex based proteomics.
ORGANISM(S): Homo Sapiens 
2020-12-11 | PXD022775 |
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