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UnknownChiral, air stable, and reliable Pd(0) precatalysts applicable to asymmetric allylic alkylation chemistry.
Not available
S-EPMC10698162 | biostudies-literature
ProteomicsQuantitative proteome analysis to map the targets of small molecule UM171
Earlier we identified the protein degradation properties of small molecule UM171 (Subramaniam et al., 2020, Blood). Here we employed quantitative proteomics approach to map the global targets of UM171. Our study revealed multiple targets including the members of CoREST complex such as RCOR1 and LSD1...
ORGANISM(S): Homo sapiens (Human) 
2023-03-30 | PXD037999 | Pride
Um171 Protein degradation. Corest 
ProteomicsQuantitative cellular proteome analysis of Fetal- and Adult-Derived MLL-Rearranged Leukemia
Infant and adult MLL-rearranged (MLLr) leukemia represents a disease with few treatment options and a dismal prognosis. Here, we present an in-depth proteomic characterization of in utero-initiated and adult-onset MLLr leukemia in a mouse model of MLL-ENL-mediated leukemogenesis. We characterize ear...
ORGANISM(S): Mus musculus (Mouse) 
2024-04-02 | PXD042249 | Pride
Adult hematopoietic progenitor Tmtpro Mll-rearranged leukemia Fetal hematopoietic progenitor 
UnknownInhibiting Focal Adhesion Kinase Ameliorates Cyst Development in Polycystin-1-Deficient Polycystic Kidney Disease in Animal Model.
Not available
S-EPMC8729842 | biostudies-literature
UnknownA pragmatic randomized clinical trial of insulin glargine 300 U/mL vs first-generation basal insulin analogues in insulin-naive adults with type 2 diabetes: 6-month outcomes of the ACHIEVE Control study.
Not available
S-EPMC7692902 | biostudies-literature
UnknownRare and Coding Region Genetic Variants Associated With Risk of Ischemic Stroke: The NHLBI Exome Sequence Project.
Not available
S-EPMC4673986 | biostudies-literature
UnknownA meta-analysis of 120 246 individuals identifies 18 new loci for fibrinogen concentration.
Not available
S-EPMC4715256 | biostudies-literature
UnknownREGEN-COV Antibody Combination and Outcomes in Outpatients with Covid-19.
Not available
S-EPMC8522800 | biostudies-literature
UnknownTGFB2 mutations cause familial thoracic aortic aneurysms and dissections associated with mild systemic features of Marfan syndrome.
Not available
S-EPMC4033668 | biostudies-literature
UnknownCommon and rare von Willebrand factor (VWF) coding variants, VWF levels, and factor VIII levels in African Americans: the NHLBI Exome Sequencing Project.
Not available
S-EPMC3724194 | biostudies-literature
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