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UnknownResearch into the mechanism of intervention of Wenjing decoction in endometriosis based on network pharmacology and molecular docking technology.
Not available
S-EPMC10470684 | biostudies-literature
UnknownCRISPR/Cas9 edited HSFA6a and HSFA6b of Arabidopsis thaliana offers ABA and osmotic stress insensitivity by modulation of ROS homeostasis.
Not available
S-EPMC7671043 | biostudies-literature
ProteomicsIdentification of BRCA2-DSS1 new partner HELZ
R-loops are dynamic three-stranded nucleic acid structures that regulate genome function but can threaten genome stability if not properly resolved. BRCA2, a key player in homologous recombination (HR), also regulates R-loops, though the mechanisms remain unclear. To uncover novel R-loop regulators,...
ORGANISM(S): Homo sapiens (Human) 
2025-12-30 | PXD066766 | Pride
Hela Biotinid-dss1 Brca2 Helz 
ProteomicsEnhanced Quantitative LC-MS/MS Analysis of N-linked Glycans Derived from Glycoproteins Using Sodium Deoxycholate Detergent
Protein glycosylation is a common protein post-translational modification (PTM) in living organisms and has been shown to associate with multiple diseases, and thus may potentially be a biomarker of such diseases. Efficient protein/glycoprotein extraction is a key step in the preparation of N-glycan...
ORGANISM(S): Homo sapiens (Human) 
2018-05-16 | PXD008687 | Pride
Acidic labile detergent Detergent removal Lc-ms/ms sample preparation N-glycomics Sodium deoxycholate 
ProteomicsProteomic raw data for ctrl HRECs, CAPSL knockdown HRECs, and CAPSL overexpression HRECs
The purpose of this project is to explore the changes in signaling pathways after CAPSL knockdown and overexpression, and to identify potential downstream target genes of CAPSL along with the signaling pathways they are involved in. Ultimately elucidating the molecular mechanisms underlying CAPSL pa...
ORGANISM(S): Homo sapiens (Human) 
2024-09-04 | PXD051696 | Pride
Hrecs  capsl  knockdown  overexpression 
ProteomicsLactylation of NAT10 promotes N4‐acetylcytidine modification on tRNASer-CGA-1-1 to boost oncogenic DNA virus KSHV reactivation
N4-acetylcytidine (ac4C), a conserved but recently rediscovered RNA modification on tRNAs, rRNAs and mRNAs, is catalyzed by N-acetyltransferase 10 (NAT10). Lysine acylation is a ubiquitous protein modification that controls protein functions. Our latest study demonstrates a NAT10-dependent ac4C modi...
ORGANISM(S): Homo Sapiens 
2024-04-26 | PXD049447 |
ProteomicsSilicon-rhodamine-enabled Identification (SeeID) for Near-Infrared Light Controlled Proximity Labeling In Vitro and In Vivo
Advancement in fluorescence imaging techniques enables the study of protein dynamics and localization with unprecedented spatiotemporal resolution. However, current imaging tools are unable to elucidate dynamic protein interactomes underlying imaging observations. In contrast, proteomics tools such ...
ORGANISM(S): Homo Sapiens Mus Musculus 
2025-08-11 | PXD067243 |
ProteomicsLong-Term Hepatitis B Virus Infection Induces Cytopathic Effects in Primary Human Hepatocytes and Can be Partially Reversed by Antiviral Therapy
Global temporal quantitative proteomic and transcriptomic analysis using long-term hepatitis B virus (HBV)-infected primary human hepatocytes uncovered extensive remodeling of host proteome and transcriptome, and revealed cytopathic effects of long-term viral replication. Metabolic-, complement-, cy...
ORGANISM(S): Homo Sapiens 
2021-08-31 | PXD028190 |
ProteomicsLong-Term Hepatitis B Virus Infection Induces Cytopathic Effects in Primary Human Hepatocytes, and Can be Partially Reversed by Antiviral Therapy
Proteomics analysis was then applied to identify genes or pathways that could be rescued by RNAi.
ORGANISM(S): Homo Sapiens 
2022-02-01 | PXD031397 |
ProteomicsPlasma proteomic and metabolomic signatures of B-ALL patients during CAR-T cell therapy
The study aimed to assess plasma proteomic and metabolomic profiling in patients with B-ALL during humanized anti-CD19-CAR-T cell therapy
ORGANISM(S): Homo Sapiens 
2023-02-24 | PXD040366 |
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