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UnknownHuman airway mast cells proliferate and acquire distinct inflammation-driven phenotypes during type 2 inflammation.
Not available
S-EPMC8362933 | biostudies-literature
UnknownAllergic inflammatory memory in human respiratory epithelial progenitor cells.
Not available
S-EPMC6133715 | biostudies-literature
UnknownExtensive Molecular and Clinical Heterogeneity in Patients With Histologically Diagnosed CNS-PNET Treated as a Single Entity: A Report From the Children's Oncology Group Randomized ACNS0332 Trial.
Not available
S-EPMC9153369 | biostudies-literature
ProteomicsTAF8 regions important for TFIID lobe B assembly are required for embryonic stem cell survival
The human general transcription factor TFIID is composed of the TATA-binding protein (TBP) and 13 TBP-associated factors (TAFs). In eukaryotic cells, TFIID is thought to nucleate RNA polymerase II (Pol II) preinitiation complex formation on all protein coding gene promoters and thus, be crucial for ...
ORGANISM(S): Homo sapiens (Human) 
2021-10-02 | PXD026575 | Pride
Embryonic stem cell (esc) Taf8 Tfiid Cxms 
ProteomicsA structural model of the human mSWI/SNF (BAF) complex bound to the nucleosome informs disease mechanisms
Mammalian SWI/SNF complexes are multi-component ATP-dependent chromatin-remodeling complexes that regulate genomic architecture. Here we present the first structural model of the human canonical BAF chromatin-remodeling complex bound to a nucleosome generated using cryo-EM, cross-linking mass spectr...
ORGANISM(S): Homo sapiens (Human) 
2021-02-10 | PXD020992 | Pride
Homology model Cryo-em Atp-dependent chromatin remodeling Nucleosome acidic patch Yeast swi/snf Mammalian swi/snf Canonical baf complex Human disease Mutations 
UnknownGranzyme K activates the entire complement cascade.
Not available
S-EPMC12180478 | biostudies-literature
UnknownWhole genome sequence analyses of brain imaging measures in the Framingham Study.
Not available
S-EPMC5772158 | biostudies-literature
UnknownGenetic studies of body mass index yield new insights for obesity biology.
Not available
S-EPMC4382211 | biostudies-literature
UnknownNew genetic loci link adipose and insulin biology to body fat distribution.
Not available
S-EPMC4338562 | biostudies-literature
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