Sort   by:  
 Page size 
ProteomicsHuman LC-MS Data in HEK293T overexpressed LATS2
LC-MS data for Enzyme Activity-Independent NANS Stabilizes LATS2 to Drive Growth and Confer Resistance to Endocrine Therapy and CDK4/6 Inhibitors in HR+/HER2- Breast Cancer
ORGANISM(S): Homo sapiens (Human) 
2025-12-14 | PXD065340 | Pride
Human lc-ms lats2 
ProteomicsPhosphopeptide mass spectrometry analysis of LATS2 identifies a second autophosphorylation site in HEK293A cells
This dataset contains phosphopeptide LC-MS/MS data generated from human LATS2 overexpressed in HEK293A cells. The study was designed to identify LATS2 phosphorylation sites and to support phosphopeptide mapping of LATS2 autophosphorylation, with particular attention to the kinase-domain CLS site. Im...
ORGANISM(S): Homo sapiens (Human) 
2026-06-29 | PXD076693 | Pride
Homo sapiens  hek293a  lats2  hippo pathway  autophosphorylation  phosphopeptide  lc-ms/ms  kinase 
ProteomicsUbiquitinylation in cancer - LATS1 but not LATS2 represses autophagy by a kinase-independent scaffold function
Samples were subjected to sonication using Bioruptor (program mode – 30 sec on, 30 sec off, 10 cycles = 10 min). Samples were sonicated till a clear solution was obtained. After a short spin (5,000 rpm for 10 sec), the samples were heated for 10 minutes at 95°C at 300 rpm in a PCR 96 heating block. ...
ORGANISM(S): Homo sapiens (Human) 
2020-01-13 | PXD013159 | Pride
Beclin Mtor Glygly 
UnknownHippo-YAP/TAZ-ROS signaling axis regulates metaflammation induced by SelenoM deficiency in high-fat diet-derived obesity.
Not available
S-EPMC12126717 | biostudies-literature
ProteomicsTargeting upstream Hippo-pathway kinases releases the scaffolder WWC1 to promote synaptic plasticity and long-term memory in mice
The localization, number, and function of postsynaptic AMPA-type glutamate receptors (AMPARs) are crucial for synaptic plasticity, a cellular correlate for learning and memory. The Hippo pathway member WWC1 is an important component of AMPAR hetero-protein complexes. However, genetic analysis sugges...
ORGANISM(S): Homo sapiens (Human) 
2024-05-03 | PXD050351 | Pride
Kibra Wwc1 Memory Kinobead Msti 
ProteomicsYAP/TAZ drives ependymoma-like tumour formation in mice
YAP1 gene fusions have been observed in a subset of paediatric ependymomas. Here we show that, ectopic expression of active nuclear YAP1 (nlsYAP5SA) in ventricular zone neural progenitor cells using conditionally-induced NEX/NeuroD6-Cre is sufficient to drive brain tumour formation in mice. Neuron...
ORGANISM(S): Mus musculus (Mouse) 
2020-05-26 | PXD018131 | Pride
Brain Mus musculus Tmt10plex Nlsyap5sa Ependymoma 
Sort   by:  
 Page size