Human glutamatergic neurons

Show results for

Unknown (586)
Genomics (124)
Transcriptomics (111)
Proteomics (15)
Genomic (1)
Methylation profiling (1)

Organisms

Homo sapiens (79)
Mus musculus (34)
Archaea (11)
Bacteria (11)
Betaherpesvirinae (11)
Borrelia (11)
Botrytis cinerea (11)
Candida albicans (11)
Clostridium perfringens (11)
Eukaryota (11)
Fungi (11)
Hepatitis B virus (11)
Herpesvirales (11)
Human betaherpesvirus 5 (11)
Influenza C virus (11)
Japanese encephalitis virus group (11)
Miscanthus x giganteus (11)
Mus musculus (11)
Danio rerio (3)
Macaca mulatta (3)
Lonchura striata (2)
Pan troglodytes (2)
synthetic construct (2)
Macaca fascicularis (1)
Caenorhabditis elegans (1)
Rattus norvegicus (1)
Drosophila melanogaster (1)
Gallus gallus (1)
Sus scrofa (1)
Synthetic plasmid (1)

Organisms

Homo sapiens (71)
Mus musculus (17)
Lonchura striata (2)
Danio rerio (2)
Synthetic plasmid (1)
Drosophila melanogaster (1)
Sus scrofa (1)

Repository

ENA (113)
geo (81)
biostudies-arrayexpress (41)
pride (11)
MassIVE (4)
dbGaP (1)
EGA (1)

Tissue

Brain (5)
Cell culture (5)
Astrocyte (1)
CNS neuron (sensu Vertebrata) (1)
Central nervous system neuron (1)
Cerebral cortex pyramidal neuron (1)
Generation of neurons (1)
Glutamatergic neuron (1)
Microglial cell (1)
Neuronal stem cell (1)
Stem cell (1)

Disease

Alzheimer's disease (2)
Normal (1)
Leigh disease (1)
Neurodegenerative disease (1)

Technology Type

Mass Spectrometry (11)
Shotgun proteomics (3)
Affinity purification coupled with mass spectrometry proteomics (2)
Bottom-up proteomics (2)
Data-dependent acquisition (2)
Data-independent acquisition (1)
SWATH MS (1)
Top-down proteomics (1)

Instrument Platform

Illumina NovaSeq 6000 (8)
Single-Cell Extraction: For enzymatic digestion, pronase (Septomyces argeus, 1 mg/mL) was applied for 25 minutes at room temperature for P0 to P8 datasets. Cells were dissociated and triturated into a single-cell suspension in ACSF supplemented with 1% fetal calf serum (FCS) and DNase (1 µL/10 mL). Trituration was performed using three glass Pasteur pipettes of decreasing diameters. For P30 datasets, enzymatic digestion and cell dissociation were carried out using the Worthington Papain Dissociation System, following the manufacturer’s instructions. Single-Nuclei Extraction: For nuclei isolation, the Hibernate™-E Medium was removed, and 500 µL of chilled 0.1X NP40 Lysis Buffer was added. Tissue was homogenized using a Pellet Pestle (15 strokes) and incubated on ice for 5 minutes. The suspension was pipette-mixed 10 times using a wide-bore pipette tip and incubated for an additional 10 minutes on ice. Following lysis, 500 µL of chilled wash buffer was added, and the mixture was pipette-mixed 5 times using a regular-bore pipette tip. The suspension was filtered through a 30 µm cell strainer into a 50 mL tube to remove debris. The filtered suspension was transferred to a 1.5 mL tube and centrifuged at 950 × g for 10 minutes at 4°C. The supernatant was carefully removed, and the nuclei pellet was retained for downstream analysis. (2)
Sequel IIe (2)
PromethION (2)
Illumina HiSeq 4000 (2)
Chromium Next GEM Chip G (1)
10X v3 (1)
Illumina NovaSeq X (1)
Illumina HiSeq 2500 (1)
Illumina HiSeq 2000 (1)
Orbitrap Eclipse (1)
Q Exactive HF-X (1)
Synapt MS (1)
TripleTOF 6600 (1)

Publication Date

2026 (23)
2022 (18)
2025 (16)
2020 (12)
2024 (11)
2023 (10)
2016 (10)
2014 (7)
2021 (7)
2011 (6)
2012 (4)
2018 (3)
2013 (2)
2007 (2)
2019 (2)
2015 (1)
2010 (1)
2009 (1)
2008 (1)

First Public Date

2025 (20)
2022 (19)
2026 (17)
2023 (12)
2024 (10)
2020 (10)
2021 (7)
2019 (5)
2018 (4)
2016 (4)
2014 (4)
2017 (1)

Study type

Transcription profiling by array (20)
RNA-seq of coding RNA from single cells (8)
RNA-seq of coding RNA (8)
ChIP-seq (2)
Comparative genomic hybridization by array (1)
RNA-seq of total RNA (1)
RNA-seq of non coding RNA (1)

Release Date

2025 (78)
2024 (71)
2023 (68)
2022 (59)
2021 (56)
2020 (52)
2019 (46)
2016 (33)
2018 (27)
2017 (26)
2015 (22)
2026 (18)
2014 (16)
2012 (12)
2011 (12)
2009 (10)
2013 (8)
2010 (4)
2008 (4)
2007 (2)
2004 (2)
2002 (1)

Lab affiliation

1) 1Mitochondrial Neuropathology laboratory, Institut de Neurociències, Universitat Autònoma de Barcelona, Bellaterra, Spain 2) Department of Cellular Biology, Physiology and Immunology, Universitat Autònoma de Barcelona, Bellaterra, Spain. (1)
Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, University of Utrecht, Padualaan 8, 3584 CH Utrecht, the Netherlands. (1)
Department of Basic and Clinical Neuroscience, The Maurice Wohl Clinical Neuroscience Institute, Institute of Psychiatry, Psychology, & Neuroscience, King’s College London, London, UK (1)
Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461, United States (1)
Department of Biochemistry, University of Otago, New Zealand (1)
Department of Physiological Genomics, Biomedical Center, Ludwig-Maximilians University, Germany (1)
IRCCS Istituto G Gaslini (1)
Institute of Human Genetics, University Hospital Cologne, Kerpener Str. 34, 50931 Cologne, Germany. Center for Molecular Medicine Cologne (CMMC), Robert-Koch-Str. 21, 50931 Cologne, Germany (1)
Institute of Physiology II, University of Freiburg Germany (1)
Zilkha Neurogenetic Institute, Keck School of Medicine, University of Southern California (1)
associate professor of neurology Institute for cell engineering Johns hopkins university school of medicine (1)

Previous page
1 / 84
You're on page 1
page 2
page 3
page 4
page 5
page ...
page 84
Next page

Sort by:

Relevance

Page size

Endogenous retrovirus activation disrupts postsynaptic organization in human glutamatergic neurons

PRJEB128139 | ENA

A functional and omics roadmap for human induced glutamatergic neuron: fine-tuning of culture conditions for pathophysiological studies

Induced glutamatergic neurons (iGluNeurons) generated via Neurogenin-2 overexpression in human pluripotent stem cells constitute a powerful model system for studying human neuronal maturation and function. Despite their growing use in disease modelling and drug screening, NGN2-based differentiation ...

ORGANISM(S): Homo sapiens (Human) Rattus norvegicus (Rat)

2026-09-14 | PXD070249 | Pride

Genome-wide transcriptome analysis of human iPSC-derived healthy control vs schizophrenia developmental glutamatergic neurons.

PRJNA763187 | ENA

Common schizophrenia risk variants are implicated in the function of glutamatergic neurons

PRJNA601202 | ENA

sAPP a neuroprotective protein in the brain has widespread effects on the proteome of human cortical neurons related to memory mechanisms.

Human glutamatergic neurons in culture were exposed to 1 nM secreted amyloid precursor protein alpha over a time course (0, 2, 6 and 24 h) and changes in the proteome were identified with SWATH-MS.

ORGANISM(S): Homo sapiens (Human)

2022-04-03 | PXD031704 | Pride

App Alzheimer’s disease Proteome. Sappa Human neuron

Schizophrenia risk gene ZNF804A controls ribosome localization and synaptogenesis in developing human neurons

Large-scale genomic screenings greatly advanced our understanding of the genetic basis of schizophrenia. However, how this translates into neurobiological functioning is not clear. Therefore, we aimed to characterize the function of robust susceptibility gene zinc finger protein 804A (ZNF804A), usin...

ORGANISM(S): Homo sapiens (Human)

2026-03-31 | PXD047788 | Pride

Ribosomes Compartment seperation assay Schizophrenia Data-independent acquisition Synaptogenesis

RNA-Seq of human neurons derived from iPS cells Reveals candidate long non-coding RNAs Involved in neurogenesis and neuropsychiatric disorders.

As a preliminary step towards applying next generation sequencing using neurons derived from patient-specific iPSCs, we have carried out an RNA-Seq analysis on control human neurons. Dramatic changes in the expression of coding genes, long non-coding RNAs (lncRNAs), pseudogenes, and splice isoforms ...

ORGANISM(S): Homo sapiens

2011-10-06 | E-GEOD-32625 | biostudies-arrayexpress

Common schizophrenia risk variants are enriched in open chromatin regions of human glutamatergic neurons.

Not available

S-EPMC7643171 | biostudies-literature

Stem cell-derived human glutamatergic neurons with pathogenic KCNQ2 variants display hyperactive bursting phenotypes

PRJNA1234669 | ENA

Impact of schizophrenia GWAS loci converge onto distinct pathways in cortical interneurons vs glutamatergic neurons during development

PRJNA763492 | ENA

Previous page
1 / 84
You're on page 1
page 2
page 3
page 4
page 5
page ...
page 84
Next page

Sort by:

Relevance

Page size

838 Results

Show results for

Organisms

Organisms

Repository

Tissue

Disease

Technology Type

Instrument Platform

Publication Date

First Public Date

Study type

Release Date

Lab affiliation

Tags

OmicsDI is part of the ELIXIR infrastructure

Tweets