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MetabolomicsRoot hair developmental regulators orchestrate drought induced microbiome changes and affect the interactions with stress alleviating Rhizobiaceae

Drought is one of the most severe abiotic stresses. However, there is a lack of genetic evidence regarding whether and how plants coordinate the dynamic assembly of the microbiome in response to drought. Through the use of mutants with enhanced or reduced root hair densities (rsl2 rsl4, hairless ...

2024-10-28 | MTBLS11360 | MetaboLights
TranscriptomicsRNAseq of organ-cultured human hair follicles exposed to MEKi (Cobimetinib)
EGFR/MEK inhibitor therapy induces a distinct inflammatory hair follicle response that includes a collapse of hair follicle immune privilege and differential modulation of IL-33 and IL-37 expression. Our findings suggest that successful future management of EGFRi/MEKi-induced folliculitis requires r...
ORGANISM(S): Homo sapiens 
2024-07-19 | E-MTAB-13454 | biostudies-arrayexpress
ProteomicsHuman hair shaft LC-MS/MS - Studies on the Proteome of Human Hair - Identification of Histones and Deamidated Keratins
The aim of this work was to define the hair proteome after extractions with both detergent and detergent-free buffers using highly sensitive proteomics technologies based on mass spectrometry.
ORGANISM(S): Homo sapiens (Human) 
2018-01-30 | PXD007224 | Pride
Human scalp hair shaft 
TranscriptomicsTranscription profiling of human hair follicles from men and women
Investigation of Gene Expression Profiling in Unstaged Head Hair Follicles Plucked from Men and Women Experiment Overall Design: Total RNA was extracted from 1-3 unstaged follicles plucked from the scalp of each of 36 adult human volunteers. The average quantifiable yield of RNA per follicle was 11...
ORGANISM(S): Homo sapiens 
2007-12-11 | E-GEOD-3058 | biostudies-arrayexpress
ProteomicsProteome of human scalp hair follicles
Proteomic analysis of hair follicles aids in basic understanding of human scalp hair biology, and it can serve as a foundation for biomarker identification and targeted therapy in precision medicine. Proteomics of scalp hair follicles in Indian population has not been reported earlier. We have perfo...
ORGANISM(S): Homo sapiens (Human) 
2026-09-28 | PXD034166 | Pride
Ontology Plucked hair follicles Proteomics Orbitrap Scalp Interactome analysis 
ProteomicsProfiling Protein Expression Levels and Genetically Variant Peptides in Human Hair From Different Body Sites
Proteins of the human hair shaft contain a wealth of information about the coding regions of the person’s genome from whom the hair is derived. Commonly found at crime scenes, hair shafts may thus provide useful forensic evidence if the information they contain can be exploited. Present experiments ...
ORGANISM(S): Homo sapiens (Human) 
2019-04-04 | PXD011732 | Pride
Protein profiling Hair shafts Genetically variant peptides Human identification 
TranscriptomicsEffects of a Closed Space Environment on Gene Expression in Hair Follicles of Astronauts in the International Space Station
In recent times, long-term stay has become a common occurrence in the International Space Station (ISS). However, adaptation to the space environment can sometimes pose physiological problems to the astronauts after their return. Therefore, it is important to develop healthcare technologies for astr...
ORGANISM(S): Homo sapiens 
2016-03-31 | E-GEOD-74708 | biostudies-arrayexpress
ProteomicsProteomic Genotyping: Using Mass Spectrometry to Infer SNP Genotypes in Pigmented and Non-Pigmented Hair
Proteomic genotyping is the use of genetically variant peptides (GVPs), detected in a forensic protein sample, to infer the genotype of corresponding non-synonymous SNP alleles in the donor’s genome. This process does not depend on the presence of accessible or useable DNA in a sample. This makes pr...
ORGANISM(S): Homo sapiens (Human) 
2020-05-27 | PXD016156 | Pride
Proteomic genotyping Hair Hair pigmentation Melanosomes Genetically variant peptides 
TranscriptomicsTranscription profiling of human stem cells enriched for hair follicle bulge cells
The human hair follicle bulge is an important niche for keratinocyte stem cells (KSCs). Elucidation of human bulge cell biology could be facilitated by analysis of global gene expression profiles and identification of unique cell-surface markers. The lack of distinctive bulge morphology in human hai...
ORGANISM(S): Homo sapiens 
2007-11-08 | E-GEOD-3419 | biostudies-arrayexpress
ProteomicsIDENTIFICATION AND CHARACTERISATION OF TAXONOMICALLY INFORMATIVE PEPTIDES BY HIGH RESOLUTION MASS SPECTROMETRY FOR SOURCE IDENTIFICATION OF TRACE HAIR
In this study a proteomics workflow was developed for the discovery and characterization of taxonomically diagnostic hair peptides. Taxa were selected with a focus on relevance to crime scene investigation. A panel of 226 taxonomically informative peptides were identified and characterized, 209 whic...
ORGANISM(S): Bos taurus (Bovine) Sus scrofa (Pig) Camelus dromedarius (Dromedary) (Arabian camel) Vicugna pacos Mus musculus (Mouse) Homo sapiens (Human) Canis lupus Oryctolagus cuniculus (Rabbit) Felis catus (Cat) (Felis silvestris catus) Cavia porcellus (Guinea pig) Rattus norvegicus (Rat) Equus caballus (Horse) 
2026-05-13 | PXD065721 | Pride
Taxonomically informative biomarkers Hair proteins Forensic proteomics Trace evidience 
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