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ModelsUhlén2015 - Human tissue-based proteome metabolic network - lung
Uhlén2015 - Human tissue-based proteome metabolic network - lung Human lung specific proteome metabolic network This model is described in the article: Tissue-based map of the human proteome Uhlén M, Fagerberg L, Hallström BM, Lindskog C, Oksvold P, Mardinoglu A, Siverts...
2015-01-28 | MODEL1411240011 | BioModels
ProteomicsNon-small cell lung cancer global proteomics
We present data of global proteomes for non-small cell lung cancer for squamous cell and adenocarcinoma, and for normal adjacent tissue.
ORGANISM(S): Homo sapiens (Human) 
2024-12-17 | PXD054390 | Pride
Human lung cancer global proteome 
MetabolomicsComparative analysis of the adaptation of Staphylococcus aureus to internalization by different types of human non-professional phagocytic host cells (NMR assay)
Staphylococcus aureus is a human pathogen that can cause a wide range of diseases. Although formerly regarded as extracellular pathogen, it has been shown that S. aureus can also be internalized by host cells and persist within these cells. In the present study, we comparatively analyzed survival an...
2015-07-01 | MTBLS102 | MetaboLights
ProteomicsQuantitative proteomics of human lung
The proteome in human lung was identified by mass spectrometry and quantified by label free method
ORGANISM(S): Homo Sapiens 
PXD036439 |
ProteomicsProteome of silenced minichromosome maintenance protein 2 with siRNA on non-small cell lung cancer H1299 cells
Lung cancer is the leading cause of cancer-related mortality. The two main lung cancer types are small cell lung cancer (SCLC) and non-SCLC (NSCLC), where NSCLC comprises about 80-85% of all lung cancer. Despite the introduction of improved treatments, the overall survival rate of lung cancer patien...
ORGANISM(S): Homo sapiens (Human) 
2018-10-26 | PXD003743 | Pride
Non small cell lung cancer h1299 cells Rna interference Proteome Minichromosome maintenance protein 2 Itraq Lc-ms/ms 
ProteomicsComparative proteome analysis across non-small cell lung cancer cell lines
Non-small cell lung cancer (NSCLC) cell lines are widely used model systems to study molecular aspects of lung cancer. Comparative and in-depth proteome expression data across many NSCLC cell lines has not been generated yet, but would be of utility for the investigation of candidate targets and mar...
ORGANISM(S): Homo sapiens (Human) 
2015-09-14 | PXD002556 | Pride
Pca Non-small cell lung cancer K-ras Silac Proteome profiling Egfr 
ProteomicsGlobal characterization of miR-574-5p decoy to CUGBP1 in human lung cancer using a mass spectrometry proteomics approach
We aimed to characterize decoy to the RNA-binding protein CUG-RNA binding protein 1 (CUGBP1 mechanism in A549 lung cancer cells. We identified several new canonical targets of CUGBP1 but those were not regulated by miR-574-5p via the decoy mechanism. This can be explained by the localization of CUG...
ORGANISM(S): Homo sapiens (Human) 
2020-03-02 | PXD016803 | Pride
Cugbp1 Mir-574-5p Human Lung cancer Mpges-1 
ProteomicsQuantitative tissue proteomics analysis of primary lung adenocarcinoma
In this study, we generated a quantitative lung tissue proteome dataset from lung adenocarcinoma and adjacent normal lung tissues by using iTRAQ labeling combined with 2D-LC-MS/MS. Based on pathway and network analyses, protein expression profiles released in the public Human Protein Atlas database,...
ORGANISM(S): Homo sapiens (Human) 
2016-05-12 | PXD004077 | Pride
Lung cancer  adenocarcinoma  lymph node metastasis  biomarkers  ero1l  nars  itraq 
ProteomicsProteome dynamics during cisplatin exposure in sensitive and resistant human lung cancer cells
Lung cancer is the leading cause of cancer-related deaths and its treatment is based in chemotherapy using platinum containing compounds, mainly cisplatin (CDDP). Many patients show resistance to CDDP leading to treatment failure. To understand the mechanisms involved in CDDP resistance in lung canc...
ORGANISM(S): Homo sapiens (Human) 
2023-03-10 | PXD021779 | Pride
Proteomics Drug resistance Boncat Cisplatin Lung cancer 
ProteomicsProteogenomic systems analysis identifies targeted therapy resistance mechanisms in EGFR-mutated lung cancer
Cancer precision medicine largely relies on knowledge about genetic aberrations in tumors and next-generation-sequencing studies have shown a high mutational complexity in many cancers. Although a large number of the observed mutations is believed to be not causally linked with cancer, the functiona...
ORGANISM(S): Homo sapiens (Human) 
2018-07-02 | PXD009996 | Pride
Lung cancer Proteomic System biology Drug resistance 
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