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TranscriptomicsA genotype-first approach for the molecular and clinical characterization of uncommon de novo microdeletion of 20q13.33
Molecular cytogenetic techniques such as microarray analysis have allowed for a “genotype-first” approach to the characterization of chromosome abnormalities: in the absence of clinical features suggestive of a specific syndrome, patients with similar copy number imbalances can be examined for commo...
ORGANISM(S): Homo sapiens 
2010-12-31 | E-GEOD-21536 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse pre-implantation development over twelve time points from the germinal vesicle (GV) stage oocyte to the late (expanded) blastocyst
The goal of the experiments was to profile and analyze gene activity during murine pre-implantation development. Samples were collected at twelve time points from the germinal vesicle (GV) stage oocyte to the late (expanded) blastocyst.
ORGANISM(S): Mus musculus 
2004-02-19 | E-MEXP-51 | biostudies-arrayexpress
UnknownSticker Shock: How Information Affects Citizen Support for Public School Funding.
Not available
S-EPMC4884814 | biostudies-literature
ProteomicsHuman Dental Pulp TAILS N-terminomics
We report the targeted analysis of the human dental pulp proteome and N-terminome using the positional proteomics technique TAILS, which allowed us to capture both naturally blocked and unblocked protein N-termini. Furthermore, by using a proteomically barely studied human tissue in combination with...
ORGANISM(S): Homo sapiens (Human) 
2015-08-18 | PXD002264 | Pride
Human Agilent g6550a q-tof Dental pulp Tails n-terminomics Lc-ms/ms 
ProteomicsPreclinical Optimization of the PI3K/Akt inhibitor Paxalisib for the Treatment of Diffuse Midline Glioma
Diffuse midline glioma (DMG) is a uniformly fatal pediatric, adolescent, and young adult cancer diagnosed in the midline structures of the brain. PI3K/Akt signaling is an overarching contributor to the poor outcomes of DMG patients due to their dependance on insulin and recurring mutations and ampli...
ORGANISM(S): Homo sapiens (Human) 
2024-02-20 | PXD036114 | Pride
Phosphoproteomics Dmg Proteogenomics Dipg Pi3k/akt Paxalisib 
TranscriptomicsTranscription profiling by array of Candida albicans populations exposed to a temperature shift from 25 degrees to 37 degrees
Seperate White and Opaque Candida albicans populations were exposed to a temperature shift from 25 degrees to 37 degrees. Samples were then harvested at various time points to follow the effects of the shift on the two cell types, particularly the opaque cell type which switches to the white cell ...
ORGANISM(S): Candida albicans 
2011-05-08 | E-MEXP-2705 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of C. albicans to identify the commintment point of the temperature induced opaque-to-white switch
This experiment is a characterization of the commitment point of the temperature induced opaque-to-white switch in the fungal pathogen Candida albicans. This experiment examines changes in the transcriptome occurring at the 50% commitment points for both the wild type and WOR1/wor1 strains in order...
ORGANISM(S): Candida albicans 
2011-07-07 | E-MEXP-2834 | biostudies-arrayexpress
ProteomicsComparative quantitative proteomic analysis of Chlamydomonas reinhardtii cells from wild-type and chimeric FNR-PSAF mutant cells
Photosynthetic linear electron transfer (LET) comprises a solar energy driven pathway tha directs electrons to the production of NADPH, via ferredoxin-NADP+ reductase (FNR), while generating a proton motive force (pmf) to drive ATP synthesis. Both NADPH and ATP are consumed for carbon fixation. Howe...
ORGANISM(S): Chlamydomonas reinhardtii 
2025-05-07 | PXD052753 | Pride
Chloroplast Cyclic electron transfer Crispr-cas9 Photosystem (ps) Let Ferredoxin-nadp+ reductase Chlamydomonas reinhardtii Psi subunit psaf Linear electron transfer Cet 
ProteomicsIntegrative multiomic analyses of dorsal root ganglia in diabetic neuropathic pain using proteomics, phosphoproteomics, and metabolomics
Diabetic peripheral neuropathy (DPN) is characterized by spontaneous pain in the extremities. Incidence of DPN continues to rise with the global diabetes epidemic. However, there remains a lack of safe, effective analgesics to control this chronic painful condition. Dorsal root ganglia (DRG) contain...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-01-09 | MSV000091027 | MassIVE
UnknownA high-resolution 3D atlas of the spectrum of tuberculous and COVID-19 lung lesions.
Not available
S-EPMC9641421 | biostudies-literature
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