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ProteomicsEffects of hypoxia-reoxygenation stress on mitochondrial proteome and bioenergetics of the hypoxia-tolerant marine bivalve Crassostrea gigas
Intermittent hypoxia is a common stressor in estuarine and coastal habitats due to the diurnal and tidal cycles of oxygen availability. Oxygen deficiency results in energy stress by limiting aerobic ATP production, while reoxygenation may lead to oxidative injury due to the excessive production of r...
ORGANISM(S): Crassostrea gigas (Pacific oyster) (Crassostrea angulata) 
2021-11-04 | PXD011365 | Pride
Hypoxia/reoxygenation Proteomics Oyster Mitochondria Lc-ms/ms 
MetabolomicsBased on the Metabolomic Approach the Energy Metabolism Responses of Oriental River Prawn Macrobrachium nipponense Hepatopancreas to Acute Hypoxia and Reoxygenation
Hypoxia represents a major physiological challenge for prawns and is a problem in aquaculture. Therefore, an understanding of the metabolic response mechanism of economically important prawn species to hypoxia and re-oxygenation is essential. However, little is known about the intrinsic mechanisms b...
2021-05-17 | MTBLS584 | MetaboLights
ProteomicsHypoxia-reoxygenation stress response in the marine facultative anaerobe Mytilus edulis
Hypoxia is a characteristic feature of marine environments and a major stressor for marine organisms inhabiting benthic and intertidal zones. Several studies have explored the responses of these organisms to hypoxic stress at the whole organism level with a focus on energy metabolism and mitochondri...
ORGANISM(S): Mytilus edulis (Blue mussel) 
2021-11-25 | PXD027955 | Pride
Hypoxia-reoxygenation Taurine Phosphoproteins Mitochondria Mussels Supercomplexes 
GenomicslncRNA SCIRT in hypoxia/reoxygenation.
lncRNA SCIRT in hypoxia/reoxygenation.
PRJNA794182 | ENA
ProteomicsProteomic investigatProteomic investigation of acute and chronic hypoxia /reoxygenation responsive hemostatic proteins and pathways in H9C2 cardiomyocyteson of acute and chronic hypoxia /reoxygenation responsive hemostatic proteins and pathways in H9C2 cardiomyocytes
Ischemic heart disease continues to rank highly among cardiovascular diseases in the world. Myocardial reperfusion (R) is provided with an effective and rapid treatment, however it can lead to fatal results as well as ischemia (I). The goal of this study was to use proteomic analysis to assess the p...
ORGANISM(S): Rattus norvegicus (Rat) 
2024-07-25 | PXD047994 | Pride
Proteomics Cardiomyocytes H9c2 Hypoxia Reoxygenation 
GenomicsRNA-seq of Caco-2 cells treated with hypoxia/reoxygenation
RNA-seq of Caco-2 cells treated with hypoxia/reoxygenation
PRJNA977633 | ENA
ProteomicsMass Spectrometry Profiling of Lysosomal IP under Normoxia and Hypoxia-Reoxygenation
This project employed TMEM192-3×Flag-mediated lysosome immunoprecipitation (Lyso-IP) followed by mass spectrometry to investigate lysosomal proteomes under normoxia and hypoxia/reoxygenation (H/R) stress. Our study focuses on the mechanisms of lysosomal renewal, revealing that damaged lysosomes unde...
ORGANISM(S): Homo sapiens (Human) 
2026-06-03 | PXD078485 | Pride
Human B-fission 
GenomicsRNA-seq of depletion of TMEM2 during Caco-2 cells treated with hypoxia/reoxygenation
RNA-seq of depletion of TMEM2 during Caco-2 cells treated with hypoxia/reoxygenation
PRJNA970808 | ENA
GenomicsTranscriptomic profiling of mouse neural stem cells after hypoxia/reoxygenation
Transcriptomic profiling of mouse neural stem cells after hypoxia/reoxygenation
PRJNA916480 | ENA
ProteomicsEffects of NMDAR on mouse hippocampal neuron (HT22) proteome expression during hypoxia/reoxygenation injury
Brain tissue is extremely sensitive to hypoxia/reoxygenation (H/R) injury, which can easily cause irreversible damage to neurons. H/R injury could induce neuronal apoptosis through glutamate-mediated excitotoxicity. N-methyl-d-aspartate receptor (NMDAR) is one of the main receptors of excitatory glu...
ORGANISM(S): Mus Musculus 
2022-08-24 | PXD036251 |
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