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ProteomicsColobanthus quitensis differential proteomics
Global warming is strongly affecting the Maritime Antarctica climate and the consequent melting of perennial snow and ice covers resulted in increased colonization by plants. Colobanthus quitensis is a vascular plant highly adapted to the harsh environmental conditions of Antarctic Peninsula and und...
ORGANISM(S): Colobanthus quitensis 
2021-07-26 | PXD027038 | Pride
Colobanthus quitensis  differential proteomic analysis  open top chambers  response to stress  temperature changes 
ProteomicsFrom Sea to Therapy: Development and analytical control of recombinant human CDKL5 production in the marine bacterium Pseudoalteromonas haloplanktis TAC125
Marine bacteria are increasingly explored as alternative microbial platforms for the production of high-value biopharmaceuticals, owing to their distinctive physiological and biochemical features. In this study, we focus on the Antarctic marine bacterium Pseudoalteromonas haloplanktis TAC125 (PhTAC1...
ORGANISM(S): Pseudoalteromonas haloplanktis 
2026-05-29 | PXD073800 | Pride
Antarctic marine bacteria  cell-factory  difficult to express proteins  elisa  hcdkl5  protein phosphorylation  pseudoalteromonas haloplanktis tac125  quality by design. 
ProteomicsCombining proteomics and machine learning to identify potential triple negative breast cancer biomarkers binding telomeric G-Quadruplex
Triple-negative breast cancer (TNBC) lacks ER, PR and HER2 expression, represents ~10–20% of invasive breast cancers, and is clinically aggressive with limited targeted treatment options. Its pronounced molecular heterogeneity challenges single-marker diagnostics, motivating the development of robus...
ORGANISM(S): Homo sapiens (Human) 
2026-05-29 | PXD072866 | Pride
Aptamers Pulldown Cancer Tnbc Gquadruplex Tumor Triple negative breast cancer Human G4 
ProteomicsCombining proteomics and machine learning to identify triple negative breast cancer biomarkers binding telomeric G-Quadruplex
Triple-negative breast cancer (TNBC) lacks ER, PR and HER2 expression, represents ~10–20% of invasive breast cancers, and is clinically aggressive with limited targeted treatment options. Its pronounced molecular heterogeneity challenges single-marker diagnostics, motivating the development of robus...
ORGANISM(S): Homo sapiens (Human) 
2026-05-29 | PXD072964 | Pride
Tel46 Tnbc Gquadruplex Cancer Breast Dna Quantitative proteomics Biomarkes 
ProteomicsSpike S1 domain interactome in non-pulmonary systems: a role beyond the receptor recognition
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes Coronavirus Disease 2019 (COVID-19), which, since 2019 in China, has rapidly become a worldwide pandemic. The aggressiveness and global spread were enhanced by the many SARS-CoV-2 variants that have been isolated up to now. These mu...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD035709 | Pride
Ap-ms Sars-cov-2 Proteomics S1 domain Interactomics Host-virus interaction Covid-19 Spike protein 
ProteomicsProteomic and degradomic signatures of extracellular matrix remodeling in calcific aortic valve
Calcific aortic valve disease (CAVD) is the most common valvular heart disease in older adults, but no medical therapy is currently able to halt or reverse its progression, partly because the molecular mechanisms of valve remodeling remain incompletely understood. Here, we aimed to dissect the extra...
ORGANISM(S): Homo sapiens (Human) 
2026-05-29 | PXD073246 | Pride
Aortic valve stenosis Extracellular matrix remodeling proteomics Calcific aortic valve disease Collagen post-translational modifications 
ProteomicsProteomic and degradomic signatures of extracellular matrix remodeling in calcific aortic valve stenotic
Calcific aortic valve disease (CAVD) is the most common valvular heart disease in older adults, but no medical therapy is currently able to halt or reverse its progression, partly because the molecular mechanisms of valve remodeling remain incompletely understood. Here, we aimed to dissect the extra...
ORGANISM(S): Homo sapiens (Human) 
2026-05-29 | PXD070758 | Pride
Calcific aortic valve disease Collagen post-translational modifications Aortic valve stenosis Extracellular matrix remodeling proteomics 
UnknownDasatinib Plus Intensive Chemotherapy in Children, Adolescents, and Young Adults With Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia: Results of Children's Oncology Group Trial AALL0622.
Not available
S-EPMC6067800 | biostudies-literature
UnknownHigh Frequency and Poor Outcome of Philadelphia Chromosome-Like Acute Lymphoblastic Leukemia in Adults.
Not available
S-EPMC5455698 | biostudies-literature
ProteomicsA multidisciplinary integrated approach for the identification and characterization of the AMP profile in Hermetia illucens hemolymph
The growing threat of antimicrobial resistance calls for alternative strategies to conventional antibiotics. Insects represent a promising source of antimicrobial peptides (AMPs) due to their potent innate immune responses. In this study, we investigated the peptide extracts from hemolymph of Hermet...
ORGANISM(S): Hermetia illucens 
2026-06-01 | PXD071144 | Pride
Antimicrobial peptides  hermetia illucens  antimicrobial resistance  proteomics  in vitro antibacterial assay  in silico prediction 
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