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Integrin alpha 5 is a key transmembrane protein that mediates cell-ECM adhesion and ECM assembly. Its activation and signaling involve both cytoplasmic and extracellular proteins. Using zebrafish somitogenesis as the physiological setting, we sought to identify activation-state-dependent Integrin al...
ORGANISM(S): Danio rerio (Zebrafish) (Brachydanio rerio) 
2025-10-13 | PXD058550 | Pride
Integrin alpha 5 is a key transmembrane protein that mediates cell-ECM adhesion and ECM assembly. Its activation and signaling involve both cytoplasmic and extracellular proteins. Using zebrafish somitogenesis as the physiological setting, we sought to identify activation-state-dependent Integrin al...
ORGANISM(S): Danio Rerio 
2025-11-10 | PXD058747 | panorama
Chemical cross-linking coupled with mass spectrometry plays an important role in unravelling protein interactions, especially weak and transient interactions. Moreover, cross-linking complements several structure determination approaches such as cryo-EM. Although several computational approaches are...
ORGANISM(S): Homo sapiens (Human) 
2016-09-27 | PXD003880 | Pride
Integrin adhesion complexes (IACs) bridge the extracellular matrix to the actin cytoskeleton and transduce signals in response to both chemical and mechanical cues. The composition, interactions, stoichiometry and topological organisation of proteins within IACs are not fully understood. To address ...
ORGANISM(S): Mus musculus (Mouse) 
2020-06-01 | PXD017241 | Pride
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