Ionising radiation

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Mass Spectrometry (11)
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Metabolite Name

[(Z)-[3-[(E)-3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoyl]oxy-1-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]sulfanylpent-4-enylidene]amino] sulfate (1)
2-Naphthalenecarboxamide, 1-hydroxy-N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]- (1)
(11R)-16-methoxy-5,7-dioxa-13-azoniapentacyclo[11.8.0.02,10.04,8.015,20]henicosa-1(13),2,4(8),9,14,16,18,20-octaene-11,17-diol (1)
(2S)-1-[(2E)-2-[(2S)-6-carboxy-2-carboxylato-2,3-dihydro-1H-pyridin-1-ium-4-ylidene]ethylidene]-5-[(3R,4S,5S,6R)-3-[(3R,4S,5S,6S)-6-carboxylato-3,4,5-trihydroxyoxan-2-yl]oxy-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-6-oxido-2,3-dihydroindol-1-ium-2-carboxylate (1)
Asp-Pro-Asp (1)
Val-Asn-Val-Asp-Glu (1)
[(2R,3S,4R,5S)-5-[4-[[(1R)-1-[(7S)-2-amino-7-methyl-4-oxo-7,8-dihydro-1H-pteridin-6-yl]ethyl]amino]phenyl]-3,4-dihydroxyoxolan-2-yl]methyl phosphate (1)
Ile-Asn-Val-Asp-Tyr (1)
Thr-Phe-Glu-Glu-Asp (1)
Ala-Arg-Asp-Glu-Thr (1)
Phe-Ala-Gly-Lys-Gln (1)
Val-Leu-Leu-Gly-Thr (1)
Ala-Gly-Pro-His-Lys (1)
8-oxido-4-oxo-1H-quinoline-2-carboxylate (1)
6-Desmethoxy hormothamnione diacetate (1)
(1R,4S,5R,7S,11S)-5-chloro-2,10-dioxatricyclo[5.3.1.04,11]undecan-4-ol (1)
Ser-Trp-Asp-Pro-Phe (1)
(1R,3R,8R,12S,13R,17R,18Z,20Z,24R,25S,26S)-12-hydroxy-17-[(1R)-1-hydroxyethyl]-5,13,25-trimethylspiro[2,10,16,23-tetraoxatetracyclo[22.2.1.03,8.08,25]heptacosa-4,18,20-triene-26,2'-oxirane]-11,22-dione (1)
Val-Glu-His-Asp (1)
Regorafenib monohydrate (1)
(1R,4aR)-8,8-dimethyl-2-oxospiro[4a,6a,7,9-tetrahydro-4H-pentaleno[1,6a-c]pyran-1,2'-oxirane]-5-carboxylate (1)
(1S,5S,6S)-5-(Hydroxymethyl)-6-(3,5-dimethoxy-4-hydroxyphenyl)-8-oxabicyclo[3.2.1]octa-3-ene-2-one (1)
(2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(5-hydroxy-8-methoxy-4-oxo-2-phenylchromen-7-yl)oxyoxane-2-carboxylate (1)
DTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose (1)
[[[(2R,3S,4R,5R)-3,4-dihydroxy-5-[6-(3-methylbut-2-enylamino)purin-9-yl]oxolan-2-yl]methoxy-oxidophosphoryl]oxy-oxidophosphoryl] hydrogen phosphate (1)
DTDP-4-oxo-2-deoxy-alpha-D-pentos-2-ene (1)
(3R,4S,9R,11R)-29-(4-hydroxyphenyl)-3-methoxy-4-methylnonacosane-9,11-diol (1)
{3-[6,9,17,19,21-pentahydroxy-5-(3-hydroxyphenyl)-18-[3,5,7-trihydroxy-2-(3-hydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-4-yl]-4,12,14-trioxapentacyclo[11.7.1.0(2),(1)(1).0(3),.0(1),(2)]henicosa-2(11),3(8),9,15(20),16,18-hexaen-13-yl]phenyl}oxidanesulfonic acid (1)
[(2S,3R,4R,5R,6S)-4,5-dihydroxy-2-[[(1S,2S,4S,5S,6R,10S)-2-(hydroxymethyl)-10-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3,9-dioxatricyclo[4.4.0.02,4]dec-7-en-5-yl]oxy]-6-methyloxan-3-yl] (E)-3-(3,4-dihydroxyphenyl)prop-2-enoate (1)
[3-[ethoxy(hydroxy)phosphoryl]oxy-2-hydroxypropyl] (9Z,12Z)-octadeca-9,12-dienoate (1)

First Public Date

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Modification

2x(15)N labeled L-lysine (1)
4 (1)
4x(15)N labeled L-arginine (1)

Study type

Transcription profiling by array (29)
RNA-seq of coding RNA (6)
Cell line - High-throughput sequencing (2)
Comparative genomic hybridization by array (2)
ChIP-seq (2)
Unknown experiment type (1)
MicroRNA profiling by high throughput sequencing (1)
DNA-seq (1)

Release Date

2022 (28)
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2000 (1)
1999 (1)

Lab affiliation

Cell matrix biology and regenerative medicine, School of biological sciences, University of manchester (2)
CRUK/MRC Oxford Institute for Radiation Oncology, Department of Oncology, University of Oxford, Oxford OX3 7DQ, UK (1)
Cambridge Centre for Proteomics, Department of Biochemistry, University of Cambridge, UK. (1)
Cell matrix biology and regenerative medicine, School of Biological Sciences, University of Manchester (1)
DNA damage responses and cancer lab Department of Human Genetics Leiden University Medical Center Eithovenweg 20 2333ZC Leiden The Netherlands (1)
Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark (1)
Genome Integrity and DNA Repair Core Group, Hungarian Centre of Excellence for Molecular Medicine (HCEMM), Szeged, H-6728, Hungary (1)
Max F. Perutz Laboratories, Mass Spectrometry Facility, University of Vienna (1)
PSE-SANTE/SERAMED, LRMED, IRSN (1)
RC Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Headington, Oxford OX3 9DS 2Edinburgh Cancer Research, CRUK Scotland Centre, Institute of Genetics and Cancer, University of Edinburgh, Crewe Road South, EH4 2XU, Edinburgh, UK (1)

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Mechanism of Blueberry Anthocyanins in Ameliorating Radiation-Induced Intestinal Injury through Gut Microbiota Modulation

Radiation-induced intestinal injury denotes structural and functional impairment of the intestines resulting directly or indirectly from ionising radiation, such as that employed in radiation therapy for malignant tumours in the abdominal or pelvic regions, within the treatment area. It is a prevale...

2026-05-29 | MTBLS14609 | MetaboLights

RNA-seq of Norwegian spruce embryos exposed to gamma radiation

Conifers such as Picea abies (Norway spruce) are among the most radiosensitive plant species, yet the molecular impact of ionising radiation on their stem cells remains poorly understood. This study examines the transcriptomic response of embryogenic stem cells to gamma radiation, focusing on mechan...

ORGANISM(S): Picea abies

2025-07-14 | E-MTAB-15297 | biostudies-arrayexpress

Mouse ESC LC-MSMS Ionising radiation

Dose-dependent (phospho) proteome responses of mouse embyronic stem cells to ionising radiation. Quantitative SILAC- and mass spectrometry-based proteomics and phosphoproteomics experiments were performe at half an hour (0.5h) and four hours (4h) after exposure to LD (0.1 Gy) and high doses (HD; 1 G...

ORGANISM(S): Mus musculus (Mouse)

2022-03-18 | PXD025343 | Pride

2 doses of ionising radiations (x-rays) -Transcriptomic analysis of effects of ionising radiation on Arabidopsis thaliana.

au09-03_gamma-irradiation - 2 doses of ionising radiations (x-rays) - Metabolic pathways involved in the response of plants to ionising radiation treatment. - Arabidopsis thaliana (Col-0) seeds were grown in Petri dishes under sterile conditions until they had 2-rosette-leaves (on average 10 days)....

ORGANISM(S): Arabidopsis thaliana

2012-02-25 | E-GEOD-35942 | biostudies-arrayexpress

Transcription profiling of human ES and keratinocyte cells in response to ionising radiation

I-131, a source of beta- and gamme radiation and the Auger electron emitter I-125 dU incorporated into nuclear DNA were compared in two cell lines , human ES cells and the keratinocyte cell line HaCaT.

ORGANISM(S): Homo sapiens

2010-10-07 | E-MEXP-1843 | biostudies-arrayexpress

Non-targeted effects of ionising radiation--implications for low dose risk.

Not available

S-EPMC4091999 | biostudies-literature

Chronic low-dose ionising radiation rates affect the hippocampal phospho-proteome of synaptogenesis in an ApoE-/--Alzheimer mouse model over 300 days of exposure

Cognitive impairments are an important side effect after radiation exposure. Yet, it comes more and more into scientific focus that ionising radiation can resemble pathologies of neurodegenerative diseases such as Alzheimer´s. Here, we used a multidisciplinary approach to elucidate the effect of chr...

ORGANISM(S): Mus musculus (Mouse)

2017-07-25 | PXD003969 | Pride

Synapse Proteomics Hippocampus Synaptic plasticity Dendritic spine Phospho-proteomics Creb

Analysis of gene co-expression networks in skin cells exposed to different doses of ionising radiation at different time points

Most studies have analysed the effects of high dose radiation such as atomic bomb survivors in Japan, people exposed during the Chernobyl nuclear accident, patients undergoing radiation therapy, uranium miners, etc. However, it has been difficult to measure and assess the risk of cancer in people ex...

ORGANISM(S): Homo sapiens

2012-02-01 | E-GEOD-29344 | biostudies-arrayexpress

2 doses of ionising radiations (x-rays) -Transcriptomic analysis of effects of ionising radiation on Arabidopsis thaliana.

ORGANISM(S): Arabidopsis thaliana

2012-02-25 | GSE35942 | GEO

Dynamic modulation of N6-methyladenosine by ionising radiation in human cells

PRJEB95941 | ENA

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