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For further identify the differentiation between latent and clinical tuberculosis (TB), we employed whole genome microarray expression profiling to study genes with significant expression change in peripheral CD4+T cells between healthy control, latent tuberculosis (LTB) and clinical tuberculosis (T...
ORGANISM(S): Homo sapiens 
To investigate and identify the potential DUBs that stabilize and interact with DDR1, we performed immunoprecipitation of endogenous DDR1 with anti-DDR1 antibody (specific IP) or anti-IgG antibody (negative control) in A549 cells followed by mass spectrometry analysis.
ORGANISM(S): Homo sapiens (Human) 
2025-09-08 | PXD065332 | Pride
The retinoblastoma protein (Rb) is a tumour suppressor best known for repressing E2F transcription factors and halting cell cycle progression1. In hormone receptor-positive (HR+) breast cancer, CDK4/6 inhibitors activate Rb by preventing its phosphorylation, forming a key component of current endocr...
ORGANISM(S): Homo sapiens (Human) 
2026-06-23 | PXD066496 | Pride
Total RNA was extracted from three partially overlapping dorsal skin layers derived from P2.5 normal (E+/E+) and recessive yellow (e/e) mice, as well as from an immortalized mouse melanocyte cell line (melan-a). Replicate samples (cy5) were labelled and co-hybridized with a reference RNA sample (cy3...
ORGANISM(S): Mus musculus 
In Saccharomyces cerevisiae short non-coding RNA (ncRNA) generated by RNA Polymerase II (Pol II) are terminated by the NRD complex consisting of Nrd1, Nab3 and Sen1. We now show that Pcf11, a component of the cleavage and polyadenylation complex (CPAC), is generally required for NRD-dependent transc...
ORGANISM(S): Saccharomyces cerevisiae 
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