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GenomicsJ774.1 mouse macrophage-like cell line: Control vs. IR or TAM or Torin1
J774.1 mouse macrophage-like cell line: Control vs. IR or TAM or Torin1
PRJNA702072 | ENA
GenomicsRNA sequencing of wild Type, Rictor-KO or GATA3-KO J774.1 cells
RNA sequencing of wild Type, Rictor-KO or GATA3-KO J774.1 cells
PRJNA702662 | ENA
TranscriptomicsJ774.1 mouse macrophage-like cell line: Control vs. IR or TAM or Torin1
Transcriptional profiling of J774.1 cells comparing control (DMSO treatment) with IR or TAM or Torin1 treated cells.
ORGANISM(S): Mus musculus 
2022-02-15 | GSE166821 | GEO
GenomicsThe effect of CTBP dehydrogenase inhibitors MTOB and 4-Cl-HIPP in J774.1 cells
The effect of CTBP dehydrogenase inhibitors MTOB and 4-Cl-HIPP in J774.1 cells
PRJNA1185200 | ENA
TranscriptomicsPolysomal, free mRNP, and total cellular mRNA of J774.1 before and after LPS stimulation
Bacterial lipopolysaccharide(LPS) dramatically activates macrophages. So far, dozen of papers indicated that many proinflammatory molecules are transcriptionaly regulated during response. Despite of this,translational regulation is not fully elucidated especially in a comprehensive fashion. In this ...
ORGANISM(S): Mus musculus 
2008-02-05 | GSE4288 | GEO
TranscriptomicsRNA sequencing of wild Type, Rictor-KO or GATA3-KO J774.1 cells
Purpose: Endosomal-lysosomal system is one of the pivotal degradation system for a varieties of extracellular substances, of which dysfunction has been indicated to be associated with cardiovascular and neurodegenerative diseases. This degradation process consists of multiple steps; uptake of extrac...
ORGANISM(S): Mus musculus 
2022-02-15 | GSE167009 | GEO
UnknownImmunomodulatory Activity of Octenyl Succinic Anhydride Modified Porang (Amorphophallus oncophyllus) Glucomannan on Mouse Macrophage-Like J774.1 Cells and Mouse Primary Peritoneal Macrophages.
Not available
S-EPMC6152250 | biostudies-literature
TranscriptomicsThe effect of CTBP dehydrogenase inhibitors MTOB and 4-Cl-HIPP in J774.1 cells
C-terminal binding proteins (CTBPs) are conserved transcriptional repressors involved in cancer and inflammation. Uniquely amongst transcriptional coregulators, CTBPs possess a functional dehydrogenase domain. Since multiple malignancies display elevated CTBP levels, CTBP inhibitors targeting this d...
ORGANISM(S): Mus musculus 
2025-02-25 | GSE281668 | GEO
ProteomicsProfiling CTBP2’s genome-wide interactome in murine macrophages during LPS-induced inflammation – oligomerization-dependent interactions
To identify oligomerization dependent interactors of C-terminal binding protein 2 (CTBP2), we stably expressed CTBP2 wild type or a monomeric mutant (CTBP2 mono: CTBP2 C140Y, N144R, R147E, L156W) in Ctbp1-/-, Ctbp2-/- J774.1 cells and profiled their genome-wide interactome in LPS conditions after 3 ...
ORGANISM(S): Mus musculus (Mouse) 
2025-06-08 | PXD063883 | Pride
Lps Macrophage J774.1 Ctbp2 Inflammation Oligomerization Mouse Chip-ms 
GenomicsMus musculus
Polysomal, free mRNP, and total cellular mRNA of J774.1 before and after LPS stimulation
PRJNA94783 | ENA
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