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ProteomicsNovel Targeted Proteomic Profiling of Potential Biomarkers in Postural Orthostatic Tachycardia Syndrome (POTS)
Postural orthostatic tachycardia syndrome (POTS) is a cardiovascular autonomic disorder leading to debilitating symptoms and the therapeutic alternatives are limited. Proteomics is a large-scale study of proteins that enables a systematic unbiased view on disease and health, allowing stratification ...
ORGANISM(S): Homo sapiens (Human) 
2022-11-24 | PXD031458 | Pride
Lc-msms Postural orthostatic tachycardia syndrome Proteomics Pots Biomarkers 
ProteomicsProject title: Endogenous AIRE-immunoprecipitation from primary human neutrophils
Autoimmune regulator (AIRE) is a transcriptional regulator. We here assess the role for AIRE in primary human neutrophils. We found that the functional role for AIRE in neutrophils is to regulate the extrinsic apoptotic pathway involving the Fas/TNFR death receptors and Cathepsin G and the expressio...
ORGANISM(S): Homo sapiens (Human) 
2024-01-25 | PXD047989 | Pride
Neutrophil Aire Human 
TranscriptomicsMolecular characterization of adult mouse subventricular zone progenitor cells during the onset of differentiation
Adult mouse subventricular zone (SVZ) neural progenitor cells (NPCs) retain the capacity to generate multiple lineages in vitro and in vivo. Thus far, the mechanisms involved in the regulation of these cells have not been well elucidated. We have carried out RNA profiling of adult SVZ cell cultures ...
ORGANISM(S): Mus musculus 
2010-07-01 | E-GEOD-4496 | biostudies-arrayexpress
ProteomicsDecoding of the surfaceome and endocytome in primary glioblastoma cells identifies potential target antigens in the hypoxic tumor nicheDecoding of the surfaceome and endocytome in primary glioblastoma cells identifies potential target antigens in the hypoxic tumor niche
Immunotherapies with antibody-drug-conjugates (ADC) and CAR-T cells, targeted at tumor surface antigens (surfaceome), currently revolutionize clinical oncology. However, target identification warrants a better understanding of the surfaceome and how it is modulated by the tumor microenvironment. Her...
ORGANISM(S): Homo sapiens (Human) 
2024-05-23 | PXD048880 | Pride
Glioblastoma Tumor antigens Proteomics Hypoxia. Immunotherapy 
UnknownProjected resurgence of COVID-19 in the United States in July-December 2021 resulting from the increased transmissibility of the Delta variant and faltering vaccination.
Not available
S-EPMC9232215 | biostudies-literature
UnknownImpact of SARS-CoV-2 vaccination of children ages 5-11 years on COVID-19 disease burden and resilience to new variants in the United States, November 2021-March 2022: A multi-model study.
Not available
S-EPMC9679449 | biostudies-literature
UnknownGenome-wide analyses of neonatal jaundice reveal a marked departure from adult bilirubin metabolism.
Not available
S-EPMC11364559 | biostudies-literature
UnknownImpact of SARS-CoV-2 vaccination of children ages 5-11 years on COVID-19 disease burden and resilience to new variants in the United States, November 2021-March 2022: a multi-model study.
Not available
S-EPMC8936106 | biostudies-literature
UnknownMultiple models for outbreak decision support in the face of uncertainty.
Not available
S-EPMC10160947 | biostudies-literature
UnknownEvaluation of the US COVID-19 Scenario Modeling Hub for informing pandemic response under uncertainty.
Not available
S-EPMC10661184 | biostudies-literature
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