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UnknownBioactive Components and Potential Mechanism Prediction of Kui Jie Kang against Ulcerative Colitis via Systematic Pharmacology and UPLC-QE-MS Analysis.
Not available
S-EPMC9239780 | biostudies-literature
UnknownPharmacokinetic-Pharmacodynamic Analysis on Inflammation Rat Model after Oral Administration of Huang Lian Jie Du Decoction.
Not available
S-EPMC4900566 | biostudies-literature
MetabolomicsMetabolomics analyses of cancer tissue from patients with colorectal cancer.
The alteration of metabolism is essential for the initiation and progression of numerous types of cancer, including colorectal cancer (CRC). Metabolomics has been used to study CRC. At present, the reprogramming of the metabolism in CRC remains to be fully elucidated. In the present study, comprehen...
2024-02-08 | MTBLS8090 | MetaboLights
MetabolomicsPRODH regultes naive pluripotency by influencing mitochondrial oxidative phosphorylation (Untargeted metabolomics)

Naïve human embryonic stem cells (hESCs) that resemble the pre-implantation epiblasts are fueled by a combination of aerobic glycolysis and oxidative phosphorylation, but their mitochondrial regulators are poorly understood. Here we report that, proline dehydrogenase (PRODH), a mitochondria-local...

2024-02-12 | MTBLS7840 | MetaboLights
ProteomicsProteomic characterization of native and decellularized rat submandibular gland scaffolds prepared using the S3T1 protocol
Salivary gland hypofunction lacks effective regenerative treatment, and organ-specific decellularized extracellular matrix scaffolds represent a promising biomaterial platform for tissue engineering. In this study, rat submandibular glands were decellularized using a rapid S3T1 workflow consisting o...
ORGANISM(S): Rattus norvegicus (Rat) 
2026-04-21 | PXD077315 | Pride
Extracellular matrix scaffold Proteomics Dia Rat Submandibular gland Salivary gland tissue engineering Decellularization Lc-ms/ms 
ProteomicsTranslational and Post-translational LC-MS of Naïve and Primed hESCs
Deciphering the regulatory network for human naïve and primed pluripotency is of fundamental theoretical and applicable significance. Here, by combining quantitative proteomics, phosphoproteomics and acetylproteomics analyses, we revealed RNA processing and translation as the most differentially-reg...
ORGANISM(S): Homo sapiens (Human) 
2021-12-10 | PXD030230 | Pride
Lc-ms Primed Human Hesc Naïve 
ProteomicsComparative phosphoproteomic analyses of OCT4 protein in hESC
This study is directed to systematically map out phosphorylation sites in OCT4 protein that are differentially phosphorylated between naïve hESCs and their primed counterparts, and to further identify the upstream kinases that phosphorylate the sites in naïve hESC-specific manner
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD033619 | Pride
Human Lc-ms/ms Hesc 
ProteomicsEndogenous OCT4 interactome in hESC
In two widely-cited OCT4-protein interactome papers, Ding et al. (Ding et al., 2012) used murine ESC nuclear extract to identify OCT4 interactome in nucleus and Pardo et al. (Pardo et al., 2010) used whole cell lysate to identify OCT4 interactome in murine ESCs. In both papers, Benzonase, a genetica...
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD033840 | Pride
Oct4 Esc Human 
MetabolomicsPRODH regultes naive pluripotency by influencing mitochondrial oxidative phosphorylation (Targeted metabolomics)

Naïve human embryonic stem cells (hESCs) that resemble the pre-implantation epiblasts are fueled by a combination of aerobic glycolysis and oxidative phosphorylation, but their mitochondrial regulators are poorly understood. Here we report that, proline dehydrogenase (PRODH), a mitochondria-local...

2024-02-12 | MTBLS7832 | MetaboLights
UnknownEnhanced electrochemical performance of li-ion battery via ultrasonic-assisted inorganic-rich and thin SEI layer.
Not available
S-EPMC10550765 | biostudies-literature
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