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UnknownUp-regulated expression of two-pore domain K+ channels, KCNK1 and KCNK2, is involved in the proliferation and migration of pulmonary arterial smooth muscle cells in pulmonary arterial hypertension.
Not available
S-EPMC10894933 | biostudies-literature
ProteomicsK2P2.1 shapes morphology and function of brain endothelial cells via actin network remodeling
K2P2.1 (gene: Kcnk2), a two-pore domain potassium channel, is an important regulator of leukocyte transmigration across the blood-brain barrier. However, the underlying molecular mechanisms remain poorly characterized. We here show that Kcnk2-/- mouse brain microvascular endothelial cells (MBMECs) s...
ORGANISM(S): Mus musculus (Mouse) 
2025-07-28 | PXD031051 | Pride
Actin remodeling Eae Kcnk2 Blood-brain-barrier Trek1 K2p2.1 Lc-ms/ms 
UnknowneQTL of KCNK2 regionally influences the brain sulcal widening: evidence from 15,597 UK Biobank participants with neuroimaging data.
Not available
S-EPMC6420450 | biostudies-literature
GenomicsTrpv4 inhibits p53-driven Dkk1 and Sost secretion in Kcnk2+ osteolineage subpopulation to rejuvenate the aged osteo-brain axis
Trpv4 inhibits p53-driven Dkk1 and Sost secretion in Kcnk2+ osteolineage subpopulation to rejuvenate the aged osteo-brain axis
PRJNA1200886 | ENA
UnknownIdentification and characterization of two zebrafish Twik related potassium channels, Kcnk2a and Kcnk2b.
Not available
S-EPMC6192994 | biostudies-literature
UnknownEffect of 158 herbal remedies on human TRPV1 and the two-pore domain potassium channels KCNK2, 3 and 9.
Not available
S-EPMC7484967 | biostudies-literature
UnknownPharmacogenetic analysis of genes implicated in rodent models of antidepressant response: association of TREK1 and treatment resistance in the STAR(*)D study.
Not available
S-EPMC10034848 | biostudies-literature
UnknownA potential role of mechano-gated potassium channels in meningioma-related seizures.
Not available
S-EPMC10582377 | biostudies-literature
UnknownThe potassium channel K<sub>2P</sub>2.1 shapes the morphology and function of brain endothelial cells via actin network remodeling.
Not available
S-EPMC12274505 | biostudies-literature
Genomicsena-DATASET-IfGH-11-05-2017-08:36:08:072-67 - samples
Clinical and genetic information of an individual with RVOT-VT and a KCNK2 (TREK1) gene mutation obtained after whole exome sequencing.
EGAD00001003328 | EGA
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