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The Hedgehog signaling pathway is essential for the maintenance and response of several types of stem cells. To study the transcriptional response of stem cells to HH signaling, we searched for proteins binding to GLI proteins, the transcriptional effectors of the HH pathway in mouse embryonic stem ...
ORGANISM(S): Mus musculus (Mouse) 
2016-02-04 | PXD002494 | Pride
Arginine methylation is a ubiquitous post-translational modification involved in many biological processes such as transcription, cell signaling and RNA splicing. Tudor domains by far are the major effector domain family for arginine methylation mark recognition. Here we characterize SART3 as a nove...
ORGANISM(S): Homo sapiens (Human) 
2024-10-17 | PXD044862 | Pride
Interpreting proteomics data remains challenging due to the large number of proteins that are quantified by modern mass spectrometry methods. Weighted gene correlation network analysis (WGCNA) can identify groups of biologically related proteins using only protein intensity values by constructing pr...
ORGANISM(S): Homo sapiens (Human) 
2022-01-27 | PXD030784 | Pride
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