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ProteomicsK-562 GalNAc-T1/2 Bump-and-hole Whole cell lysate proteomics data
Engineered GalNAc-T glycosyltransferases were used to incorporate a chemically modified GalNAc analog into the glycoproteins on the cell surface of K-562 cells. The chemical modification included a bioorthogonal alkyne tag that allowed for introduction of a clickable, acid-cleavable biotin-picolyl-a...
ORGANISM(S): Homo sapiens (Human) 
2020-04-22 | PXD017989 | Pride
Human Mucin Bioorthogonal Galnac-t Click Glycoprotein K-562 
TranscriptomicsOverlapping and unique responses of E. coli to adverse conditions
In the present study we have determined the global gene expression and biomolecular composition in an Escherichia coli model strain exposed to ten adverse conditions (sodium chloride, ethanol, glycerol, two acids (hydrochloric acid and acetic acid), sodium hydroxide, heat (46°C) and cold (15°C) as...
ORGANISM(S): Escherichia coli str. K-12 substr. MG1655 
2010-05-18 | E-GEOD-11041 | biostudies-arrayexpress
UnknownMitogenic modulation of Ca2+ -activated K+ channels in proliferating A7r5 vascular smooth muscle cells.
Not available
S-EPMC1751930 | biostudies-literature
UnknownDown-regulation of KCa2.3 channels causes erectile dysfunction in mice.
Not available
S-EPMC5476588 | biostudies-literature
UnknownSafety of switching from vitamin K antagonists to dabigatran or rivaroxaban in daily care--results from the Dresden NOAC registry.
Not available
S-EPMC4239984 | biostudies-literature
UnknownNew positive Ca2+-activated K+ channel gating modulators with selectivity for KCa3.1.
Not available
S-EPMC4152908 | biostudies-literature
UnknownGenetic deficit of KCa 3.1 channels protects against pulmonary circulatory collapse induced by TRPV4 channel activation.
Not available
S-EPMC4562510 | biostudies-literature
ProteomicsLimited proteolysis of SARS-CoV-2 Spike treated at pH 2 or pH 7
SARS-CoV-2 is a respiratory virus spreading via aerosol particles. Aerosol particles can exhibit extreme environmental conditions affecting contained viruses, including acidic pH. Here, we study how harsh pH conditions, such as pH 2, can affect the structure of Spike, which is the main protein media...
ORGANISM(S): Homo sapiens (Human) Severe acute respiratory syndrome coronavirus 2 
2025-07-17 | PXD064612 | Pride
Sars-cov-2 Lc-ms Spike Acidic ph Lip 
UnknownMutations in PA2491 (mexS) promote MexT-dependent mexEF-oprN expression and multidrug resistance in a clinical strain of Pseudomonas aeruginosa.
Not available
S-EPMC545639 | biostudies-literature
UnknownA novel beta-peptidyl aminopeptidase (BapA) from strain 3-2W4 cleaves peptide bonds of synthetic beta-tri- and beta-dipeptides.
Not available
S-EPMC1196161 | biostudies-literature
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